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Sex Differences In Cognitive Decline In Mild Cognitive Impairment And Alzheimer's Disease, Juliann Thompson
Sex Differences In Cognitive Decline In Mild Cognitive Impairment And Alzheimer's Disease, Juliann Thompson
Theses and Dissertations
Alzheimer's disease (AD) is the most common form of dementia and results in progressive cognitive decline, particularly in regards to memory (National Institute on Aging, 2012). Prior research has shown sex differences in brain-atrophy rates of AD patients, with women experiencing a higher rate of progression in volume reduction (Skup et al., 2011). This suggests that there may also be differences in cognitive functioning between sexes, particularly in the rate of cognitive decline with a more rapid disease progression for dementing females compared to dementing males. The current study monitored memory function longitudinally in approximately 200 total participants, 100 with …
The Effect Of Sleep-Dependent Consolidation On Pattern Separation And Pattern Completion In Delayed Retrieval, Jesse Ray James
The Effect Of Sleep-Dependent Consolidation On Pattern Separation And Pattern Completion In Delayed Retrieval, Jesse Ray James
Theses and Dissertations
While people sleep, the brain replays the same neural firings that resulted from waking activities that day. This results in greater memory strength following a sleeping delay than a waking delay. The current project built upon this fact in a series of three experiments. Experiment 1. Although previous research has demonstrated a benefit of sleep to memory strength, the literature has not established the impact of sleep on memory specificity. Computational models of medial temporal lobe function posit that discrimination and generalization across similar memories are accomplished through processes known as pattern separation and pattern completion, respectively. To discover whether …
The Longitudinal Stability Of Memory In Males With Autism Spectrum Disorder, Alexander J. Cramond
The Longitudinal Stability Of Memory In Males With Autism Spectrum Disorder, Alexander J. Cramond
Theses and Dissertations
Previous research has demonstrated mixed evidence on impaired memory functioning in autism spectrum disorder (ASD), with the only consensus that there appears to be much heterogeneity. In addition, no research to date has examined the stability of memory in ASD. This study examined the stability of memory function in ASD compared to typically developing age-matched controls. Participants were administered the Test of Memory and Learning (TOMAL) twice, three years apart, in an established longitudinal NIH-supported investigation of ASD. Based on available research contrasting memory development in healthy individuals versus those with ASD, it was hypothesized that memory performance in the …
The Neural Correlates Of Retrospective Memory Monitoring: Convergent Findings From Erp And Fmri, Jeremy Clark Roper
The Neural Correlates Of Retrospective Memory Monitoring: Convergent Findings From Erp And Fmri, Jeremy Clark Roper
Theses and Dissertations
Monitoring the accuracy of memory is an automatic but essential process of memory encoding and retrieval. Retrospective memory confidence judgments are making effective and efficient decisions based on one's memories. The neural processes involved in retrospective confidence ratings were investigated with EEG and fMRI using a recognition memory task designed such that participants also rated their confidence in their memory response. Correct trials (hits and correct rejections) were examined for differences related to the participants' level of confidence in their response. There were significant differences in electrophysiological activity (in the FN400 and the late parietal component) associated with confidence rating, …