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Glycogen Synthase Kinase-3Β: An Investigation Of The Novel Serine 389 Phosphorylation Site, Brendan Deegan Hare
Glycogen Synthase Kinase-3Β: An Investigation Of The Novel Serine 389 Phosphorylation Site, Brendan Deegan Hare
Graduate College Dissertations and Theses
Stress associated psychiatric disorders such as depression, anxiety, and post-traumatic stress disorder affect a large proportion of the population. Reductions in the complexity of neuronal morphology and reduced neurogenesis are commonly observed outcomes following stress exposure in rodent models and may represent a mechanism for the reduced brain volume in stress sensitive regions such as the hippocampus observed in individuals diagnosed with stress associated disorders. Multiple lines of evidence suggest that glycogen synthase kinase (GSK)-B may play a role in the neurodegenerative phenotype observed following stress exposure. GSK3B is atypical in that it is inhibited by phosphorylation. This inhibitory phosphorylation …
A Randomized Pilot Trial: An Internet-Based Mind/Body Intervention To Mitigate Anxiety In Women Experiencing Infertility, Jessica Clifton
A Randomized Pilot Trial: An Internet-Based Mind/Body Intervention To Mitigate Anxiety In Women Experiencing Infertility, Jessica Clifton
Graduate College Dissertations and Theses
Infertility is a frequently occurring chronic health condition, which often persists throughout the reproductive years. Heightened anxiety symptoms often are comorbid with infertility diagnoses. Women experiencing infertility, and particularly those with anxiety symptoms, characterize an emerging population that deserves special attention. However, women experiencing infertility have identified barriers to seeking psychotherapy (e.g., fears of being dismissed from fertility treatment and/or stigmatized). Consequently, women diagnosed with infertility need a psychotherapy that not only can reduce these symptoms, but can also be private and convenient. The current study translated an empirically tested in-person mind/body protocol into an internet-based intervention to suit the …