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Psychology

Theses/Dissertations

2007

Virginia Commonwealth University

Smoking

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The Effects Of Transdermal Nicotine On Tobacco/Nicotine Withdrawal And Concurrently Administered Cigarettes In Women And Men, Betha A. Kleykamp Jan 2007

The Effects Of Transdermal Nicotine On Tobacco/Nicotine Withdrawal And Concurrently Administered Cigarettes In Women And Men, Betha A. Kleykamp

Theses and Dissertations

Transdermal nicotine (TN) is a smoking cessation pharmacotherapy thought to work by suppressing tobacco/nicotine withdrawal and reducing the effect of a concurrently smoked tobacco cigarette. Clinical trials suggest that TN may be less efficacious for women. This study explored the possibility of gender differences in response to transdermal nicotine in 54 women and 70 men. Participants completed four within-subject, double-blind, randomized sessions corresponding to 0, 7, 14, and 21 mg TN and 4-hrs after TN application smoked an own-brand cigarette. Prior to session onset participants completed ≥ 8 hours of verified tobacco cigarette abstinence (i.e., expired air carbon monoxide levels …


Comparison Of Three Methods For Measuring Smoking Behavior, Melissa D. Blank Jan 2007

Comparison Of Three Methods For Measuring Smoking Behavior, Melissa D. Blank

Theses and Dissertations

Understanding the factors that influence regular tobacco use often involves detailed assessment of individuals' smoking behavior (i.e., puff topography), including measuring puff number, volume, duration, and inter-puff interval (IPI) via mouthpiece-based, computerized devices. For example, puff topography measurement has been used to study smoking cessation medications, as well as to demonstrate brand-induced changes in smoking behavior. However, some research suggests that the use of a mouthpiece to evaluate puff topography may alter natural smoking behavior. Thus, this study was designed to compare topography measurement using mouthpiece-based methods (i.e., desktop and portable computerized devices) to methods that do not use a …