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Alterations In Resting State Functional Connectivity Associated With Alcohol Use Severity And Impulsivity In A Community Sample, Elena R. Stein
Alterations In Resting State Functional Connectivity Associated With Alcohol Use Severity And Impulsivity In A Community Sample, Elena R. Stein
Psychology ETDs
Alcohol Use Disorder (AUD) is characterized by neurocognitive and behavioral impairments including the multidimensional construct of impulsivity. Increased impulsivity is both a risk factor for, and a consequence of problematic alcohol use. Individuals with AUD exhibit alterations in neural circuitry when compared to those who do not have AUD. These circuit-level changes in AUD may underlie the difficulties that these individuals experience with heightened impulsivity. The present study uses data-driven resting state functional connectivity (rsFC) methodology to examine the differences in intrinsic functional networks between individuals with AUD and those who are social drinkers (SD). Participants in this secondary data …
The Effects Of Prenatal Alcohol Exposure On The Resting State Functional Brain Connectivity In A Sample Of Individuals With Fetal Alcohol Spectrum Disorder, Carlos I. Rodriguez
The Effects Of Prenatal Alcohol Exposure On The Resting State Functional Brain Connectivity In A Sample Of Individuals With Fetal Alcohol Spectrum Disorder, Carlos I. Rodriguez
Psychology ETDs
It is well established that alcohol exposure during prenatal development can lead to a heterogeneous and wide ranging set of morphological and neurobehavioral deficits that are collectively known as Fetal Alcohol Spectrum Disorders (FASDs). Previous neuroimaging research conducted on individuals with FASD has primarily employed graph-theoretical based analysis methods on functional imaging data to elucidate the impact of prenatal alcohol on brain connectivity. This study applied a widely used computational algorithm, group independent components analysis (gICA), to extract coherent sets of voxels that were correlated with one another as a measure of functional network connectivity (FNC) in a sample of …
Relationship Between Structure And Functional Connectivity Within The Default Mode Network, Andrei A. Vakhtin
Relationship Between Structure And Functional Connectivity Within The Default Mode Network, Andrei A. Vakhtin
Psychology ETDs
We proposed a novel measure of conceptualizing dynamic functional network connectivity (FNC) in the human brain using flexibility of functional connectivity (fFC), which captures the variance of functional connectivity across time. In task-free fMRI scans (N = 122), this measure was demonstrated to correspond to the underlying structural connectivity (SC) within the default mode network (DMN), while static functional connectivity (sFC) did so to a relatively low degree. As SC likely does not develop to facilitate task-free brain function, but rather to integrate information during cognitive engagement, we argue that fFC can estimate the potential functional connectivity exhibited outside of …