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Psychology

Theses/Dissertations

DePaul University

Chronic fatigue syndrome

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Small-World Network Analysis Of Cortical Connectivity In Chronic Fatigue Syndrome Using Eeg, Mark Alan Zinn Jun 2019

Small-World Network Analysis Of Cortical Connectivity In Chronic Fatigue Syndrome Using Eeg, Mark Alan Zinn

College of Science and Health Theses and Dissertations

The primary aim of this thesis was to explore the relationship between electroencephalography (qEEG) and brain system dysregulation in people with Chronic Fatigue Syndrome (CFS). EEG recordings were taken from an archival dataset of 30 subjects, 15 people with CFS and 15 healthy controls (HCs), evaluated during an eye-closed resting state condition. Exact low resolution electromagnetic tomography (eLORETA) was applied to the qEEG data to estimate cortical sources and perform functional connectivity analysis assessing the strength of time-varying signals between all pairwise cortical regions of interest. To obtain a comprehensive view of local and global processing, eLORETA lagged coherence was ...


Investigating Post-Exertional Malaise As A Core Symptom Of Myalgic Encephalomyelitis And Chronic Fatigue Syndrome: A Meta-Analytic Approach, Abigail A. Brown Aug 2017

Investigating Post-Exertional Malaise As A Core Symptom Of Myalgic Encephalomyelitis And Chronic Fatigue Syndrome: A Meta-Analytic Approach, Abigail A. Brown

College of Science and Health Theses and Dissertations

Efforts to establish a reliable and valid case definition for myalgic encephalomyelitis and chronic fatigue syndrome (ME and CFS) have been complicated by an over-reliance on clinical consensus, and inconsistent application of established case definitions by researchers across study sites. This has resulted in the absence of an empirically-based case definition for ME and CFS, as well as failed replication studies on potential diagnostic tests and biomarkers. One step toward an empirically-driven case definition is determining which symptoms best discriminate between patients with ME and CFS versus controls. Post-exertional malaise (PEM) is considered a cardinal symptom of ME and CFS ...


A Reexamination Of The Cognitive Behavioral Model Of Chronic Fatigue Syndrome: Investigating The Cogency Of The Model’S Behavioral Pathway, Madison Sunnquist Nov 2016

A Reexamination Of The Cognitive Behavioral Model Of Chronic Fatigue Syndrome: Investigating The Cogency Of The Model’S Behavioral Pathway, Madison Sunnquist

College of Science and Health Theses and Dissertations

Cognitive behavioral theories of chronic fatigue syndrome (CFS) assert that cognitions and behaviors perpetuate the fatigue and impairment that individuals with CFS experience (Wessely, Butler, Chalder, & David, 1991). Vercoulen and colleagues (1998) utilized structural equation modeling to empirically develop a cognitive behavioral model of CFS. The resulting model indicated that attributing symptoms to a physical cause, focusing on symptoms, and feeling less control over symptoms were associated with increased fatigue. Additionally, individuals who attributed symptoms to a physical cause reported lower activity levels and more fatigue and impairment. However, in an attempt to replicate this model, Song and Jason (2005) demonstrated that the model displayed inadequate fit statistics for a well-characterized group of individuals with CFS; the model resulted in appropriate fit for individuals with chronic fatigue from psychiatric conditions. Despite uncertainty surrounding the model’s validity, it continues to be cited to support the application of cognitive behavioral and graded exercise therapies to individuals with CFS (White et al., 2011). The current study utilized second-stage conditional process modeling (i.e., moderated mediation) to reexamine the behavioral pathway of the Vercoulen et al. (1998) model. This pathway is characterized by ...


Effects Of Timeframe On The Recall Reliability Of Me/Cfs Symptoms, Meredyth Evans Aug 2012

Effects Of Timeframe On The Recall Reliability Of Me/Cfs Symptoms, Meredyth Evans

College of Science and Health Theses and Dissertations

This study served as an investigation of the effects of symptom stability, timeframe length, and momentary symptom severity on the recall reliability of symptoms experienced by individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). ME/CFS symptoms were assessed at four recall timeframes (right now, the past week, the past month, and the past six months) and at two assessment points. Analyses revealed that test-retest reliability was significantly stronger for recall of post-exertlonal malaise (PEM), headaches, and memory problems, when these symptoms were perceived to be stable over time rather than variable. It was also revealed that the optimal ...