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Psychology

Western Michigan University

Theses/Dissertations

2020

Delay discounting

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The Effects Of Low Dose Lysergic Acid Diethylamide Administration In A Rodent Model Of Delay Discounting, Robert J. Kohler Jun 2020

The Effects Of Low Dose Lysergic Acid Diethylamide Administration In A Rodent Model Of Delay Discounting, Robert J. Kohler

Dissertations

The resurgence of Lysergic Acid Diethylamide (LSD) as a therapeutic tool requires a revival in research, both basic and clinical, to bridge gaps in knowledge left from a previous generation of work. Currently, no study has been published with the intent of establishing optimal microdose concentrations of LSD in an animal model. In the present study, rats were administered a range of LSD doses to quantify potential augmentations in choice behavior in a rodent model of delay discounting. In the first experiment, rats were administered LSD (20 or 40 μg/kg, i.p.) or saline at the start of terminal baseline training …