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Electroosmotic Flow Of Viscoelastic Fluid In A Nanochannel Connecting Two Reservoirs, Lanju Mei, Shizhi Qian Nov 2019

Electroosmotic Flow Of Viscoelastic Fluid In A Nanochannel Connecting Two Reservoirs, Lanju Mei, Shizhi Qian

Mechanical & Aerospace Engineering Faculty Publications

Electroosmotic flow (EOF) of viscoelastic fluid with Linear Phan-Thien–Tanner (LPTT) constitutive model in a nanochannel connecting two reservoirs is numerically studied. For the first time, the influence of viscoelasticity on the EOF and the ionic conductance in the micro-nanofluidic interconnect system, with consideration of the electrical double layers (EDLs), is investigated. Regardless of the bulk salt concentration, significant enhancement of the flow rate is observed for viscoelastic fluid compared to the Newtonian fluid, due to the shear thinning effect. An increase in the ionic conductance of the nanochannel occurs for the viscoelastic fluid. The enhancement of the ionic conductance ...


Dynamic Response Modeling Of High-Speed Planing Craft With Enforced Acceleration, Gene Hou, Brain Johnson, Jonathan Degroff, Steven Trenor, Jennifer Michaeli Oct 2019

Dynamic Response Modeling Of High-Speed Planing Craft With Enforced Acceleration, Gene Hou, Brain Johnson, Jonathan Degroff, Steven Trenor, Jennifer Michaeli

Mechanical & Aerospace Engineering Faculty Publications

An approach is investigated in this study for structural dynamic analysis of a high-speed planing hull, in which the pointwise acceleration data collected from sea trials are enforced as base excitation. The paper first performed the full boat analysis of an 11-meter high speed craft for a period of one wave impact selected from each of nine seakeeping runs. The sea trial acceleration data collected from 11 accelerometers placed close to the centerline and the keel are enforced as input, while those from 3 accelerometers placed around the pilot cabin are selected for validation. The substructure dynamic analysis of the ...


Effect Of The Physical Micro-Environment On Cell Adhesion And Force Exertion, Mohamad Eftekharjoo Oct 2019

Effect Of The Physical Micro-Environment On Cell Adhesion And Force Exertion, Mohamad Eftekharjoo

Mechanical & Aerospace Engineering Theses & Dissertations

Physical characteristics of the microenvironment, such as geometry and stiffness, influence cell adhesion and contractile forces. Here, we determined how these physical factors influenced cell force exertion and adhesion in two specific contexts that have broad relevance.

Fibroblasts are cells in connective tissues that interact with a fibrous extracellular matrix (ECM) that have a predominantly one-dimensional (1D) (fibrillar) geometry. However, it has been unclear as to how the 1D nature of the fibrillar ECM influences the forces exerted by fibroblasts. Here, we used fibroblast cells adherent on fibronectin lines on polyacrylamide (PAA) gels of stiffness 13 and 45 kPa to ...


Extension Of A Penalty Method For Numerically Solving Constrained Multibody Dynamic Problems, Troy Newhart Oct 2019

Extension Of A Penalty Method For Numerically Solving Constrained Multibody Dynamic Problems, Troy Newhart

Mechanical & Aerospace Engineering Theses & Dissertations

Numerical analysis of constrained static and multibody dynamic systems has become an integral part of engineering analysis with the continued improvements in technology and software availability. Many methods currently exist for numerically solving constrained static and dynamic systems. The applicability of a penalty method for constrained static solutions is observed in many academic texts and papers. The appeal for using a penalty method in statics pertains to its ease of implementation, computational suitability, and accuracy. This thesis extends a static penalty method for use with constrained multibody dynamics to observe if the penalty method’s benefits are similar for a ...


Computational Analysis And Design Optimization Of Convective Pcr Devices, Jung Il Shu Jul 2019

Computational Analysis And Design Optimization Of Convective Pcr Devices, Jung Il Shu

Mechanical & Aerospace Engineering Theses & Dissertations

Polymerase Chain Reaction (PCR) is a relatively novel technique to amplify a few copies of DNA to a detectable level. PCR has already become common in biomedical research, criminal forensics, molecular archaeology, and so on. Many have attempted to develop PCR devices in numerous types for the purpose of the lab-on-chip (LOC) or point-of-care (POC). To use PCR devices for POC lab testing, the price must be lower, and the performance should be comparable to the lab devices. For current practices with the existing methods, the price is pushed up higher partially due to too much dependence on numerous developmental ...


Endogenous Force Transmission Between Epithelial Cells And A Role For Α-Catenin, Sandeep Dumbali Jul 2019

Endogenous Force Transmission Between Epithelial Cells And A Role For Α-Catenin, Sandeep Dumbali

Mechanical & Aerospace Engineering Theses & Dissertations

In epithelial tissues, epithelial cells adhere to each other as well as to the underlying extra-cellular matrix (ECM). E-cadherin-based intercellular junctions play an important role in tissue integrity. These junctions experience cell-generated mechanical forces via apparent adaptor proteins such as beta (β) catenin, alpha (α) catenin and vinculin. Abnormalities in these junctions may result in skin related diseases and cancers. Here, I devised methods to determine the endogenous intercellular force within cell pairs as well as in large epithelial islands. I further ascertained the factors that affect the level of inter-cellular tension.

Experiments with pairs of epithelial cells exogenously expressing ...


Unsupervised-Learning Assisted Artificial Neural Network For Optimization, Varun Kote Jul 2019

Unsupervised-Learning Assisted Artificial Neural Network For Optimization, Varun Kote

Mechanical & Aerospace Engineering Theses & Dissertations

Innovations in computer technology made way for Computational Fluid Dynamics (CFD) into engineering, which supported the development of new designs by reducing the cost and time by lowering the dependency on experimentation. There is a further need to make the process of development more efficient. One such technology is Artificial Intelligence. In this thesis, we explore the application of Artificial Intelligence (AI) in CFD and how it can improve the process of development.

AI is used as a buzz word for the mechanism which can learn by itself and make the decision accordingly. Machine learning (ML) is a subset of ...


Off Axis Compressive Response Of Ice-Templated Ceramics, Rahul Kumar Jujjavarapu Apr 2019

Off Axis Compressive Response Of Ice-Templated Ceramics, Rahul Kumar Jujjavarapu

Mechanical & Aerospace Engineering Theses & Dissertations

The off-axis compressive behavior of ice-templated ceramic was analyzed using experimental results and micro-mechanical model simulation. Ice-templated ceramics is a versatile processing technique used to manufacture anisotropic ceramic foam by exploiting the anisotropic growth characteristics and lamellar morphology. The ice-templating process results in processing-structure-property relationships determined by the microstructure. The processed alumina samples which were later manufactured by water jet machine from the freeze casting were tested under quasi-static off-axis loading conditions and were used to determine the mechanical properties of the material. Digital image correlation (DIC) was used to measure the strain response of ice-templated ceramic under off-axis loading ...


Characterization And Optimization Of A Propeller Test Stand, Colin Bruce Leighton Benjamin Apr 2019

Characterization And Optimization Of A Propeller Test Stand, Colin Bruce Leighton Benjamin

Mechanical & Aerospace Engineering Theses & Dissertations

In recent history, there has been a rapid rise in the use of drones, and they are expanding in popularity each year. The widespread use and future capabilities of these unmanned aerial vehicles (UAVs) will call for increased study and classification of propellers to maximize their performance. As a result, it is necessary to have continuity in the development, maximization, and optimization of propeller test stand’s capability to collect accurate and precise measurements. It is of significant advantage to have the capability of accurately characterizing a propeller based on its thrust and torque. In this study, a propeller test ...


Design And Manufacture Of An Inertial Cascade Impactor For Industrial Hygiene Purposes, Hector Joel Gortaire Apr 2019

Design And Manufacture Of An Inertial Cascade Impactor For Industrial Hygiene Purposes, Hector Joel Gortaire

Mechanical & Aerospace Engineering Theses & Dissertations

Inertial cascade impactors are devices commonly used for industrial hygiene and pharmaceutical studies. Their main purpose is to separate particulate matter suspended in aerosols according to their sizes, which can vary from over 10 µm to 0.5 µm. Their versatility and ease of operation make them suitable for on-site sampling; however, designing them requires a careful consideration of the different geometric parameters that characterize them.

In this thesis, a 5-stage inertial cascade impactor was designed, modelled, constructed, and tested. The main design parameter was the volumetric flow rate, 40 l/min, which was provided by a vacuum pump. By ...


Comparison Of Support Methods For Static Aerodynamic Testing And Validation Of A Magnetic Suspension And Balance System, Cameron K. Neill Apr 2019

Comparison Of Support Methods For Static Aerodynamic Testing And Validation Of A Magnetic Suspension And Balance System, Cameron K. Neill

Mechanical & Aerospace Engineering Theses & Dissertations

Magnetic suspension wind tunnels offer an alternative to traditional physical support methods. They allow for the collection of support interference free data and broader dynamic test capabilities than existing methods. Determination of dynamic aerodynamic characteristics is a crucial portion of the design of new re-entry capsules. A NASA initiative restored the 6-inch Magnetic Suspension and Balance System to support the design of a new MSBS for a supersonic wind tunnel. Before a new MSBS can be constructed, the characteristics of the current MSBS must be examined.

This thesis discusses the calibration and validation of the 6-inch MSBS. After calibration, three ...


Numerical Study On The Dynamic Process Of Single Plume Flow In Thermal Convection With Polymers, Jian-Ping Cheng, Wei-Hua Cai, Hong-Na Zhang, Feng-Chen Li, Lian Shen, Shi-Zhi Qian Jan 2019

Numerical Study On The Dynamic Process Of Single Plume Flow In Thermal Convection With Polymers, Jian-Ping Cheng, Wei-Hua Cai, Hong-Na Zhang, Feng-Chen Li, Lian Shen, Shi-Zhi Qian

Mechanical & Aerospace Engineering Faculty Publications

A direct numerical simulation of single plume flow in thermal convection with polymers was carried out in a domain with 1:3 as the width to height ratio. The heat transport ability is weakened by adding polymers within the here-investigated governing parameter range. However, it is promoted when the maximum polymer extension L is increased. The distribution of vertical velocity and temperature indicates that the plume in the polymer solution case is speeded up and widens bigger as compared to that in the Newtonian fluid case. Inside the plume, polymer chains tend to release energy at the position where the ...