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Nanoparticle Formation And Coating Using Supercritical Fluids, Abhijit Aniruddha Gokhale
Nanoparticle Formation And Coating Using Supercritical Fluids, Abhijit Aniruddha Gokhale
Dissertations
Jet breakup phenomenon and nanoparticle formation
The focus of this dissertation is to study the SAS process to manufacture nanoparticles with minimum agglomeration, controlled size and size distribution. Solution jet breakup and solvent evaporation into supercritical fluid (SC CO2) is studied using high speed charged coupled device (CCD) camera facilitated with double shot particle image veloimetry (PIV) laser and a high pressure view cell. Particles formation using SAS is studied. Polyvinylpyrrolidone (PVP) particles are formed using micron size capillary nozzles and combination of thermodynamically good and poor solvents in order to achieve nano-sized particles with reduced agglomeration and …