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Penalized Integrative Analysis Of High-Dimensional Omics Data, Shuangge Ma
Penalized Integrative Analysis Of High-Dimensional Omics Data, Shuangge Ma
Shuangge Ma
No abstract provided.
Incorporating Network Structure In Integrative Analysis Of Cancer Prognosis Data, Shuangge Ma
Incorporating Network Structure In Integrative Analysis Of Cancer Prognosis Data, Shuangge Ma
Shuangge Ma
In high-throughput cancer genomic studies, markers identified from the analysis of single datasets may have unsatisfactory properties because of low sample sizes. Integrative analysis pools and analyzes raw data from multiple studies, and can effectively increase sample size and lead to improved marker identification results. In this study, we consider the integrative analysis of multiple high-throughput cancer prognosis studies. In the existing integrative analysis studies, the interplay among genes, which can be described using the network structure, has not been effectively accounted for. In network analysis, tightly-connected nodes (genes) are more likely to have related biological functions and similar regression …
Risk Factors Of Follicular Lymphoma, Shuangge Ma
Health Insurance Coverage And Impact: A Survey In Three Cities In China, Shuangge Ma
Health Insurance Coverage And Impact: A Survey In Three Cities In China, Shuangge Ma
Shuangge Ma
No abstract provided.
Integrative Analysis Of Multiple Cancer Genomic Datasets Under The Heterogeneity Model, Shuangge Ma
Integrative Analysis Of Multiple Cancer Genomic Datasets Under The Heterogeneity Model, Shuangge Ma
Shuangge Ma
No abstract provided.
Health Insurance Coverage, Medical Expenditure And Coping Strategy: Evidence From Taiwan, Shuangge Ma
Health Insurance Coverage, Medical Expenditure And Coping Strategy: Evidence From Taiwan, Shuangge Ma
Shuangge Ma
No abstract provided.
Impact Of Illness And Medical Expenditure On Household Consumptions: A Survey In Western China, Shuangge Ma
Impact Of Illness And Medical Expenditure On Household Consumptions: A Survey In Western China, Shuangge Ma
Shuangge Ma
No abstract provided.
Identification Of Gene-Environment Interactions In Cancer Prognosis Studies Using Penalization, Shuangge Ma
Identification Of Gene-Environment Interactions In Cancer Prognosis Studies Using Penalization, Shuangge Ma
Shuangge Ma
High-throughput cancer studies have been extensively conducted, searching for genetic risk factors independently associated with prognosis beyond clinical and environmental risk factors. Many studies have shown that the gene-environment interactions may have important implications. Some of the existing methods, such as the commonly adopted single-marker analysis, may be limited in that they cannot accommodate the joint effects of a large number of genetic markers or use ineffective marker identification techniques. In this study, we analyze cancer prognosis studies, and adopt the AFT (accelerated failure time) model to describe survival. A weighted least squares approach, which has the lowest computational cost, …
Integrative Analysis Of Cancer Genomic Data, Shuangge Ma
Integrative Analysis Of Cancer Genomic Data, Shuangge Ma
Shuangge Ma
In the past decade, we have witnessed a period of unparallel development in the field of cancer genomics. To address the same or similar biomedical questions, multiple cancer genomic studies have been independently designed and conducted. Cancer gene signatures identified from analysis of individual datasets often have low reproducibility. A cost-effective way of improving reproducibility is to conduct integrative analysis of datasets from multiple studies with comparable designs. To properly integrate multiple studies and conduct integrative analysis, we need to access various public data warehouses, retrieve experiment protocols and raw data, evaluate individual studies and select those with comparable designs, …
A Tale Of Two Streets: Incorporating Grouping Structure In High Dimensional Data Mining, Shuangge Ma
A Tale Of Two Streets: Incorporating Grouping Structure In High Dimensional Data Mining, Shuangge Ma
Shuangge Ma
No abstract provided.