Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Entire DC Network
Pre-Analytical Variations Affecting Inr Measurement For Dose Tailoring Of Anticoagulants., Samir Nabhan Shamma
Pre-Analytical Variations Affecting Inr Measurement For Dose Tailoring Of Anticoagulants., Samir Nabhan Shamma
Theses and Dissertations
Although warfarin (WRN) has been used as oral anticoagulant therapy for over 60 years, it remains a challenge to use in clinical practice since several factors may complicate WRN response which expressed is in international normalized ratio (INR). Numerous patient related variations may affect the adequacy of the assay interpretation which may lead to into poor clinical management. This study aims investigating the impact of age, sex, hemoglobin, packed cell volume (PCV), and albumin levels as well as patient adherence and drug-drug interactions (DDI) on coagulation monitoring results. INR was recorded in patients under WRN maintenance therapy (n=96). Hemoglobin, PCV …