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The Use Of Molecular Dynamics Simulations To Predict Thymine Dimer Formation In Histone Bound Dna, Emily Ann Brune Heinsen Apr 2017

The Use Of Molecular Dynamics Simulations To Predict Thymine Dimer Formation In Histone Bound Dna, Emily Ann Brune Heinsen

CUP Undergraduate Research

Thymine dimers are the major lesions in DNA that are caused by environmental conditions that can lead to apoptosis or can become carcinogenic (Schreier, et al., 2007). These dimers form when the pi electrons of one thymine in a neighboring thymine pair is excited by a photon from UV light, and occurs on the picosecond time scale (Schreier, et al., 2007). Due to the ultrafast nature of this reaction, the thymines must be in proper conformation prior to excitation in order for the reaction to take place. The proper conformation for the reaction has been found to occur when the …


Joint Ncaa Division I And Ii National Championship Finals, Rachel D. Jacobson Jan 2016

Joint Ncaa Division I And Ii National Championship Finals, Rachel D. Jacobson

Master of Arts in Sport Management

The following thesis discussed a potential future event consisting of a joint National Collegiate Athletic Association (NCAA) National Volleyball Championship involving the top two Division I teams and the top two Division II teams, each playing for their own national title. Before such an event can take place, what is needed is a realistic budget, a careful marketing strategy keeping in mind the ten P's, a plan to motivate employees, a safe environment for spectators and participants, and an ethical framework for team preparation limits.


2015 6a Minnesota State High School Prep Bowl, Joe Steinert Jan 2016

2015 6a Minnesota State High School Prep Bowl, Joe Steinert

Master of Arts in Sport Management

The Minnesota State High School League (MSHSL) is in charge of all high school athletics in the state of Minnesota. The MSHSL is in charge of putting on tournaments and championship games for all high school sports. This paper focuses on the 2015 high school football championship game for section 6A. Within this paper are seven chapters about the MSHSL and the 6A championship game called the Prep Bowl. The seven chapters are history of the MSHSL, introduction to the 2015 Prep Bowl game, a marketing plan around the 6A Prep Bowl game, proper ways to retain high end coaches, …


2018 Super Bowl, Tony Dehler Jan 2016

2018 Super Bowl, Tony Dehler

Master of Arts in Sport Management

This paper is dedicated to the Super Bowl that will be held in Minneapolis, Minnesota in February of 2018. It introduces the organization responsible for the planning of the event, the event itself; as well as describes the venue in which the game will be played. The paper also includes marketing strategies for the event, suggestions to minimize risks, methods to manage employees, and discusses an ethical issue dealing with the event, as well as a personal reflection on the project and program.


Extracellular Matrix Breakdown Blocks Repair And Regeneration Following Preterm Brain Injury, Rachel Siltman, Stephen Black, Taasin Srivastava Jan 2016

Extracellular Matrix Breakdown Blocks Repair And Regeneration Following Preterm Brain Injury, Rachel Siltman, Stephen Black, Taasin Srivastava

CUP Undergraduate Research

No abstract provided.


Boston Marathon, Erin Basavage Jan 2015

Boston Marathon, Erin Basavage

Master of Arts in Sport Management

The thesis started with the first chapter introducing the Boston Athletic Association (B.A.A.) and the history within their organization. The B.A.A. mission statement and what they stand for was also represented. The second chapter describes the specific details of the Boston Marathon event. Chapter Three provided a marketing plan for the Boston Marathon. The third chapter also highlights the purpose, product, project market, position, package, price, promotion, promise, personal selling, and place. In Chapter Four a plan to motivate and retain high performance employees was explained and implemented. A risk management plan specific to the Boston Marathon made up the …


Opening Ceremony Of The Olympics, Haley Holmes Jan 2015

Opening Ceremony Of The Olympics, Haley Holmes

Master of Arts in Sport Management

The most competitive athletes from across the world come together every four years to battle for the gold medal. The Olympics began in 1896, in Athens, Greece, and has become a worldwide tradition ever since. Organizing the Opening Ceremony of the Olympics takes a special team, as well as many extraordinary managers, that can handle the pressure, stay positive, and communicate with the various culture and language differences. The Opening Ceremony of the Olympics has been my choice of research topic for the past eighteen months, examining all phases and the event as a whole. Cover the history, marketing plan, …


National Collegiate Athletic Association (Ncaa) Division I Men's Basketball Final Tour, Leah Mccall Jan 2015

National Collegiate Athletic Association (Ncaa) Division I Men's Basketball Final Tour, Leah Mccall

Master of Arts in Sport Management

Intercollegiate athletic competitions have been taking place for well over 150 years. The National Collegiate Athletic Association (NCAA) was created to oversee and regulate member school athletic competitions. The NCAA has three athletic divisions, Division I, II, and III. The NCAA currently hosts eighty-nine championships each year. This writing focuses on one of those contests, the NCAA Division I Men's Basketball Final Four. In particular, this writing focuses on the 75th Anniversary Division I Men's Basketball Final Four held in Atlanta, Georgia, in 2013. Specifically, this writing looks at what it takes to become a host city for the contest, …


2015 Major League Baseball All-Star Game, Mick Conrad Sawinski Jan 2015

2015 Major League Baseball All-Star Game, Mick Conrad Sawinski

Master of Arts in Sport Management

This capstone looks specifically at the planning, and execution of the 2015 Major League Baseball All-Star Game. Covering all aspects from marketing, financial planning, sports law and more, this project breaks down baseball's mid-summer classic from a professional sport management perspective.


Ncaa Fencing Championship, Zachary Moss Jan 2015

Ncaa Fencing Championship, Zachary Moss

Master of Arts in Sport Management

This paper examined the many aspects of planning, organizing, and managing a sporting event. Specifically, it focused on the management of the 2019 NCAA Fencing Championships utilizing Welsh-Ryan Arena at Northwestern University as the host site. Every aspect of the event is examined beginning with the organization responsible for it, going through the structure of the event itself, outlining a marketing plan for the event, analyzing the management of employees and volunteers, discussing of potential risks associated with the facility for this event, analyzing ethical concerns of the event itself, and concluding with personal reflection from the paper's author. Included …


Ncaa Division I Men's Basketball Final Four, Patrick Rydeen Jan 2015

Ncaa Division I Men's Basketball Final Four, Patrick Rydeen

Master of Arts in Sport Management

The capstone project analyzed and presented insight into the NCAA Division I Men's Basketball Tournament, including a view of the financing, marketing, event management, while also giving a view of a major ethical dilemma that the NCAA faces. The tournament has evolved in the over 75 years it has been played to become a leading event for the NCAA and a major factor in the infrastructure of the organization as a whole. The nature of the event, namely the size and the rotating venues, created a major need for a strong risk management plan to ensure the safety of everyone …


Optical Properties Of Secondary Organic Aerosols, Felisha Imholt, Ryan Caylor, Matthew Wise, John Shilling Jan 2014

Optical Properties Of Secondary Organic Aerosols, Felisha Imholt, Ryan Caylor, Matthew Wise, John Shilling

CUP Undergraduate Research

It is well known that the increased warming effect due to greenhouse gases is a major environmental concern. While the amount of solar radiation absorbed by greenhouse gases is known to a high certainty, the amount absorbed by secondary organic aerosols (SOA) is not. The experimental procedure used to measure the amount of radiation absorbed by SOA was optimized using fulvic acid. The optimized method was then used to measure how much radiation SOA absorb between ~200 and 800 nm. Using this data, mass absorption coefficient (MAC) values at 405 nm and imaginary refractive indexes (k) were calculated. These values …


Composition And Optical Properties Of Secondary Organic Aerosol Particles, Felisha Imholt, Ryan Caylor, Matthew Wise, John Shilling Jan 2014

Composition And Optical Properties Of Secondary Organic Aerosol Particles, Felisha Imholt, Ryan Caylor, Matthew Wise, John Shilling

CUP Undergraduate Research

Research Questions:

  • What is the chemical composition of SOA?
  • Does SOA absorb UV/Vis radiation?
  • If SOA does absorb UV/Vis radiation, how strong of an absorber is it?


Composition Of Secondary Organic Aerosols, Ryan Caylor, Felisha Imholt, Matthew Wise, John Shilling Jan 2014

Composition Of Secondary Organic Aerosols, Ryan Caylor, Felisha Imholt, Matthew Wise, John Shilling

CUP Undergraduate Research

The enhanced greenhouse effect is considered one our greatest global environmental problems. The amount of radiation absorbed by greenhouse gases is known to high certainty. However, absorbance from atmospheric aerosols particles is not. This study was conducted to determine the chemical composition of secondary organic aerosol particles (SOA) and to determine the compositional effect on their optical properties. The SOA were created in a temperature controlled chamber at Pacific Northwest National Laboratory (PNNL) in Richland, WA and collected on filters. The SOA were then analyzed for chemical composition using Fourier Transform Spectroscopy (FTIR). Analysis of the IR spectra revealed specific …


Optical Properties Of Secondary Organic Aerosols Using Ultraviolet/Visible Spectroscopy, Felisha Imholt Jan 2014

Optical Properties Of Secondary Organic Aerosols Using Ultraviolet/Visible Spectroscopy, Felisha Imholt

CUP Undergraduate Research

It is well known that the increased warming effect due to greenhouse gases is a major environmental concern. While the amount of solar radiation absorbed by greenhouse gases is known to a high certainty, the amount absorbed by secondary organic aerosols (SOA) is not. Our study aimed to discover how much radiation SOA particles absorb between ~200 and 800 nm. The SOA were created in one of two temperature controlled Teflon chambers within Dr. John Shilling’s lab at PNNL and were collected on 47 mm Teflon filters. We used an ultraviolet-visible (UV/Vis) spectrometer equipped with a liquid waveguide capillary flow …


2013 Ii Cu Suri (Common Poster), Vanessa Selimovic, Loriann Reese, Ruthie Nelson, Emma Sleeman, Hibery Ho, Maria Polozova Jan 2013

2013 Ii Cu Suri (Common Poster), Vanessa Selimovic, Loriann Reese, Ruthie Nelson, Emma Sleeman, Hibery Ho, Maria Polozova

CUP Undergraduate Research

A common poster providing information for several research projects: aerosol particles, deoxycytidine kinase, squaraine rotaxanes, glycol nucleic acied, and Kombucha.


Progress Toward Removal Of The Purification Tag In A Putative Toxin Protein Via Site-Specific Mutagenesis And Proteolytic Cleavage, Joanna L. Fridlund, Bethany G. Taylor, Michael H. Godsey Jan 2011

Progress Toward Removal Of The Purification Tag In A Putative Toxin Protein Via Site-Specific Mutagenesis And Proteolytic Cleavage, Joanna L. Fridlund, Bethany G. Taylor, Michael H. Godsey

CUP Undergraduate Research

Putative toxin protein BC_2332, isolated from Bacillus cereus, which is a relative of Bacillus anthracis, shows similarity in the active site to ADP-ribosylating proteins present in cholera and diphtheria. Preliminary attempts to measure the activity of the putative toxin were unsuccessful leading to the hypothesis that the purification tag is hindering the activity. This hypothesis is supported by crystal structure analysis showing the putative active site occupied by the purification tag. Our objective was to remove the purification tag, via two different methods, in order to relieve potential inhibition. Both methods have faced obstacles and the work is continuing.