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Investigating Differential Methylation In Apis Mellifera Worker Bee Sub-Castes, Ethan Wainblat
Investigating Differential Methylation In Apis Mellifera Worker Bee Sub-Castes, Ethan Wainblat
Biology
DNA can undergo epigenetic modification at cytosine nucleotides by the addition of a methyl group (CH3). These alterations, which are frequently located within the exons in social insects, may regulate transcription and/or splicing of genes. I analyzed the methylome at two developmental stages of the worker caste in the honey bee (Apis mellifera), specifically the nurse stage and the forager stage. The methylation appeared to be mostly in exons relative to the introns and exons. I then examined genome wide methylation between the two sub-castes and noticed twenty-one (21) differentially methylated genes and seventy-one (71) differentially methylated regions. The forager …