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Functionalization Of Linear Poly(Ethylenimine) As Dna-Binding Polymer For Gene Therapy Application, Thanaphorn Suk-In Jun 2017

Functionalization Of Linear Poly(Ethylenimine) As Dna-Binding Polymer For Gene Therapy Application, Thanaphorn Suk-In

Biology

Gene therapy is a technique used to combat diseases by correcting the defective gene responsible for the disease to alleviate its symptoms and restore normal function to the defective gene. Gene therapy uses vectors to deliver a functional copy of the defective gene targeted towards the defective cell to replace the defective gene with the functional one via gene transfer (1). Over the years, gene delivery vectors available for gene therapy have gradually evolved, leading to the development of new and better vectors for gene delivery. These advances contribute largely to the growing successes of gene therapy and its application …