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Malignant Catarrhal Fever Viruses In Tennessee Ruminants, Robin Lynn Cissell
Malignant Catarrhal Fever Viruses In Tennessee Ruminants, Robin Lynn Cissell
Doctoral Dissertations
Malignant catarrhal fever (MCF) is a lymphoproliferative and inflammatory syndrome affecting primarily ruminant species. The disease, which is often fatal, is most often described as affecting bovids and cervids. No vaccines are available for prevention of MCFV infection. The primary method to control spread of disease is to prevent contact between carriers and clinically susceptible species. There is no known method to control infection of malignant catarrhal fever virus-white-tailed deer variant (MCFV-WTD), as the carrier animal of this virus is unknown.
To determine the prevalence of malignant catarrhal fever viruses in Tennessee ruminant populations, blood and/or lymph node samples were …
Methicillin Resistance In Staphylococcus Pseudintermedius, Chad Christopher Black
Methicillin Resistance In Staphylococcus Pseudintermedius, Chad Christopher Black
Doctoral Dissertations
Staphylococcus pseudintermedius affecting dogs is analogous to S. aureus on humans, acting as both normal flora and opportunistic pathogen. Methicillin resistance in S. pseudintermedius is recent, with the first documented occurrence of an isolate bearing the methicillin resistance gene, mecA, in 1999. This gene encodes penicillin binding protein 2a, which renders all beta-lactam drugs ineffective and functions as a “gateway” antibiotic resistance determinant. In the presence of ineffective antibiotics, opportunities for mutational events and acquisition of mobile genetic elements increase as microbial densities increase, often leading to multi-drug resistance. Methicillin-resistant S. pseudintermedius (MRSP) infections have become increasingly common. For …
Model Or Meal? Farm Animal Populations As Models For Infectious Diseases Of Humans, Cristina Lanzas, P Ayscue, R Ivanek, Y T. Grohn
Model Or Meal? Farm Animal Populations As Models For Infectious Diseases Of Humans, Cristina Lanzas, P Ayscue, R Ivanek, Y T. Grohn
Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences
In recent decades, theory addressing the processes that underlie the dynamics of infectious diseases has progressed considerably. Unfortunately, the availability of empirical data to evaluate these theories has not grown at the same pace. Although laboratory animals have been widely used as models at the organism level, they have been less appropriate for addressing issues at the population level. However, farm animal populations can provide empirical models to study infectious diseases at the population level.