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Technology and Innovation

University of Texas at Tyler

2007

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Electrostatic Charge Polarity Effect On Respiratory Deposition In The Glass Bead Tracheobronchial Airways Model, Mohammed Ali, Malay K. Mazumder, Rama N. Reddy, Mariofanna Milanova, Jing Zhang, Alexandru S. Biris Jan 2007

Electrostatic Charge Polarity Effect On Respiratory Deposition In The Glass Bead Tracheobronchial Airways Model, Mohammed Ali, Malay K. Mazumder, Rama N. Reddy, Mariofanna Milanova, Jing Zhang, Alexandru S. Biris

Technology Faculty Publications and Presentations

The effects of unipolar and bipolar electrostatic charges on the deposition efficiency of therapeutic aerosols in the physical model of human tracheobronchial (TB) airways have been investigated. Respirable size aerosol particles were generated by a commonly prescribed and commercially available nebulizer and charged by a corona charger and then their size and charge distributions were characterized by an Electronic Single ParticleAerodynamic Relaxation Time analyzer to study the drug aerosol particles' deposition pattern. The experiments were performed with a glass bead tracheobronchial model (GBTBM) (physical model) which was designed and developed based upon widely used and adopted dichotomous lung morphometric data …