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Induction Of Nocebo Effects By Verbal Suggestions During The Caloric Test, Abbey Weist

Dissertations, 2020-current

The caloric test is the most frequently performed vestibular diagnostic test and is considered the “gold-standard” for the assessment of the peripheral vestibular system. Using a warm or cool stimulus, the caloric test alters the temperature gradient in the vestibular system resulting in nausea and dizziness. The nocebo effect is a phenomenon that can occur when negative expectations result in negative effects. No study has examined whether expectations of nausea and dizziness during the caloric test enhance the experience of unwanted symptoms. The purpose of this investigation was to determine whether a nocebo response can be elicited during the caloric …

Hearing Studies In Old Mice: The Effect Of Pre-Pulse Inhibition On The Acoustic Startle Response, Ashley B. Hillyard, Nicolette S. Chuss

Senior Honors Projects, 2010-2019

The purpose of this study pertains to hearing in the species Peromyscus maniculatus (deer mice) — specifically their responses to a startling sound. Approximately seven mice were tested between four and five years of age, approaching the lifespan of this species. By means of an accelerometer, which measures a reflexive, motor response, the mice were presented with an acoustic startle-eliciting stimulus (SES) — that is a loud, startling, unexpected sound. During the study, the mice were also presented with a softer, less-intense stimulus — known as a pre-pulse — slightly before the more intense sound. This pre-pulse stimulus was in …

Distractions In Hearing: Measuring Impulsivity In Service Members With A Mtbi, Kathleen Margaret Chopra

Dissertations, 2014-2019

One of the cognitive symptoms associated with the diagnosis of a mild traumatic brain injury (mTBI) is the degradation of focus and attention. This pilot study was designed to quantify examples of such capabilities in Service Members diagnosed with mTBI and to compare their abilities to peers without an mTBI diagnosis. Specifically, we compared participant groups on their false alarm rates and thresholds for contralateral and informational masking tasks to document the participants’ ability to focus and detect an auditory stimulus in the presence of distracting maskers. In this study, comparing the overall performance of Service Members, with and without …

Development And Deployment Of A Small Stereo-Hearing Testing System: Two Manuscripts, Sofia A. Ganev

Dissertations, 2014-2019

MANUSCRIPT #1 TITLE

Development of a Deployable Stereo-Hearing System

ABSTRACT

Objective: To investigate the effectiveness and efficiency of a portable stereo-hearing testing system with the intent of deployment for data collection in future studies. We quantify sound localization accuracy and speech-in-noise thresholds comparing unilateral (such as single-sided deafness) and bilateral subjects. We desired to design a small, inexpensive system that would show a large effect size between binaural and monaural subjects in a variety of stereo hearing tasks.

Methods: Subjects were tested on localization accuracy and speech understanding in noise using a laboratory-made stereo-hearing testing device. For the …

Variability In Clinically Measured Wideband Acoustic Immittance Over Time In Young And Old Adults, Allison G. Mcgrath

Dissertations, 2014-2019

Wideband acoustic immittance (WAI) measures of the middle ear have the potential to increase our ability to detect changes in the middle ear transfer function not seen using traditional tympanometry. In order to use this new tool diagnostically we must first understand its normal clinical variability. The present study aimed to investigate the variability that occurs when wideband acoustic immittance (WAI) is measured clinically within subjects as a function of subject age, as a function of time, and as a function of pressure. A total of thirty-six ears from eighteen subjects were studied (n=18 young adults ears, n=18 older adult …

Examining Monaural And Binaural Measures Of Phase-Locking As A Function Of Age, Larissa M. Heckler

Dissertations, 2014-2019

Understanding speech in the presence of background noise is a common complaint of middle-aged and older listeners with clinically normal audiograms. There is great interest in understanding how age-related changes in auditory physiology make it harder for older adults to understand speech in difficult listening situations, compared to young listeners. It was recently reported that middle-aged and older normal-hearing listeners showed frequency-dependent, age-related declines in the behavioral and physiological detection of interaural phase differences (Grose & Mamo, 2010; Ross et al, 2007). There is also evidence of an age-related, frequency-dependent decline in the frequency-following response (FFR) (Clinard et al., 2010), …