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Brooding Deficits In Memory: Focusing Attention Improves Subsequent Recall, Paula T. Hertel, Amanda A. Benbow, E. Geraerts
Brooding Deficits In Memory: Focusing Attention Improves Subsequent Recall, Paula T. Hertel, Amanda A. Benbow, E. Geraerts
Psychology Faculty Research
Ruminative habits of thought about one’s problems and the resulting consequences are correlated with symptoms of depression and cognitive biases (Nolen-Hoeksema, Wisco, & Lyubomirsky, 2008). In our orienting task, brooders and nonbrooders concentrated on self-focusing phrases while they were also exposed to neutral target words. On each trial in the unfocused condition, participants saw and then reported the target before concentrating on the phrase; in the focused condition, the target was reported after phrase concentration. A brooding-related deficit on a subsequent unexpected test of free and forced recall was obtained in the unfocused condition only. Brooders recalled more successfully in …
Practice Effects In A Longitudinal, Multi-Center Alzheimer's Disease Prevention Clinical Trial, Erin L. Abner, Brandon C. Dennis, Melissa J. Mathews, Marta S. Mendiondo, Allison Caban-Holt, Richard J. Kryscio, Frederick A. Schmitt, John J. Crowley
Practice Effects In A Longitudinal, Multi-Center Alzheimer's Disease Prevention Clinical Trial, Erin L. Abner, Brandon C. Dennis, Melissa J. Mathews, Marta S. Mendiondo, Allison Caban-Holt, Richard J. Kryscio, Frederick A. Schmitt, John J. Crowley
Sanders-Brown Center on Aging Faculty Publications
BACKGROUND: Practice effects are a known threat to reliability and validity in clinical trials. Few studies have investigated the potential influence of practice on repeated screening measures in longitudinal clinical trials with a focus on dementia prevention. The current study investigates whether practice effects exist on a screening measure commonly used in aging research, the Memory Impairment Screen (MIS).
METHODS: The PREADViSE trial is a clinical intervention study evaluating the efficacy of vitamin E and selenium for Alzheimer's disease prevention. Participants are screened annually for incident dementia with the MIS. Participants with baseline and three consecutive follow-ups who made less …
Cusp Catastrophe Models For Cognitive Workload And Fatigue In A Verbally Cued Pictorial Memory Task, Stephen J. Guastello, Henry Boeh, Michael Schimmels, Hillary Gorin, Samuel Huschen, Erin Davis, Natalie E. Peters, Megan Fabisch, Kirsten Poston
Cusp Catastrophe Models For Cognitive Workload And Fatigue In A Verbally Cued Pictorial Memory Task, Stephen J. Guastello, Henry Boeh, Michael Schimmels, Hillary Gorin, Samuel Huschen, Erin Davis, Natalie E. Peters, Megan Fabisch, Kirsten Poston
Psychology Faculty Research and Publications
Objective: The aim of this study was to evaluate two cusp catastrophe models for cognitive workload and fatigue. They share similar cubic polynomial structures but derive from different underlying processes and contain variables that contribute to flexibility with respect to load and the ability to compensate for fatigue.
Background: Cognitive workload and fatigue both have a negative impact on performance and have been difficult to separate. Extended time on task can produce fatigue, but it can also produce a positive effect from learning or automaticity.
Method: In this two-part experiment, 129 undergraduates performed tasks involving spelling, arithmetic, memory, and visual …
Hippocampal Theta And Gamma: Effects Of Aging, Environmental Change, Cholinergic Activation And Learning, Matthew D. Howe
Hippocampal Theta And Gamma: Effects Of Aging, Environmental Change, Cholinergic Activation And Learning, Matthew D. Howe
Honors Scholar Theses
During aging, hippocampal functioning is impaired; specifically aged humans and rats show reduced performance on spatial memory tasks. An age-related reduction in the neurotransmitter acetylcholine has been postulated to underlie this impairment. Rhythmic oscillations (theta, gamma) may serve to synchronize activity within the hippocampus and across the brain during learning; these may also change with aging.
To determine what aspects of oscillation are important for memory processing, the effects of aging, encountering a novel situation, learning a new task and cholinergic system activation (with physostigmine) were examined. Both age groups showed increased theta, but not gamma activity when encoding a …
Lithium Treatment Of Appswdi/Nos2−/− Mice Leads To Reduced Hyperphosphorylated Tau, Increased Amyloid Deposition And Altered Inflammatory Phenotype, Tiffany L. Sudduth, Joan G. Wilson, Angela Everhart, Carol A. Colton, Donna M. Wilcock
Lithium Treatment Of Appswdi/Nos2−/− Mice Leads To Reduced Hyperphosphorylated Tau, Increased Amyloid Deposition And Altered Inflammatory Phenotype, Tiffany L. Sudduth, Joan G. Wilson, Angela Everhart, Carol A. Colton, Donna M. Wilcock
Sanders-Brown Center on Aging Faculty Publications
Lithium is an anti-psychotic that has been shown to prevent the hyperphosphorylation of tau protein through the inhibition of glycogen-synthase kinase 3-beta (GSK3β). We recently developed a mouse model that progresses from amyloid pathology to tau pathology and neurodegeneration due to the genetic deletion of NOS2 in an APP transgenic mouse; the APPSwDI/NOS2-/- mouse. Because this mouse develops tau pathology, amyloid pathology and neuronal loss we were interested in the effect anti-tau therapy would have on amyloid pathology, learning and memory. We administered lithium in the diets of APPSwDI/NOS2-/- mice for a period of eight months, followed by water maze …
The Impact Of Sleep Quality On Cognitive Functioning In Parkinson's Disease, Karina Stavitsky, Sandra Neargarder, Yelena Bogdanova, Patrick Mcnamara, Alice Cronin-Golomb
The Impact Of Sleep Quality On Cognitive Functioning In Parkinson's Disease, Karina Stavitsky, Sandra Neargarder, Yelena Bogdanova, Patrick Mcnamara, Alice Cronin-Golomb
Psychology Faculty Publications
In healthy individuals and those with insomnia, poor sleep quality is associated with decrements in performance on tests of cognition, especially executive function. Sleep disturbances and cognitive deficits are both prevalent in Parkinson's disease (PD). Sleep problems occur in over 75% of patients, with sleep fragmentation and decreased sleep efficiency being the most common sleep complaints, but their relation to cognition is unknown. We examined the association between sleep quality and cognition in PD. In 35 non-demented individuals with PD and 18 normal control adults (NC), sleep was measured using 24-hr wrist actigraphy over 7 days. Cognitive domains tested included …
Age And Premorbid Intelligence Suppress Complaint-Performance Congruency In Raw Score Measures Of Memory, Matthew Merema, Craig Speelman, Elizabeth Kaczmarek, Jonathan Foster
Age And Premorbid Intelligence Suppress Complaint-Performance Congruency In Raw Score Measures Of Memory, Matthew Merema, Craig Speelman, Elizabeth Kaczmarek, Jonathan Foster
Research outputs 2012
Background: We aimed to examine the role of age and premorbid intelligence (IQ) in suppressing the relationship between subjective memory complaints (SMCs) and raw score memory performance. Methods: We used a community sample of older adults aged 66"90 years (N = 121) to test whether the inclusion of age and a premorbid IQ measure in multiple regression analyses increased semipartial correlations of raw score memory performance in predicting SMCs. Rank contrast correlations were also carried out to observe how age and premorbid IQ are related to complaint"performance congruency. Measures utilized in the study included the Memory Functioning Questionnaire (for SMCs), …
Effects Of Δ9-Tetrahydrocannabinol Administration On Human Encoding And Recall Memory Function: A Pharmacological Fmri Study, Matthijs G. Bossong, Gerry Jager, Hendrika H. Van Hell, Lineke Zuurman, J Martijn Jansma, Mitul A. Mehta, Joop M. A Van Gerven, Rene S. Kahn, Nick F. Ramsey
Effects Of Δ9-Tetrahydrocannabinol Administration On Human Encoding And Recall Memory Function: A Pharmacological Fmri Study, Matthijs G. Bossong, Gerry Jager, Hendrika H. Van Hell, Lineke Zuurman, J Martijn Jansma, Mitul A. Mehta, Joop M. A Van Gerven, Rene S. Kahn, Nick F. Ramsey
Faculty of Social Sciences - Papers (Archive)
Deficits in memory function are an incapacitating aspect of various psychiatric and neurological disorders. Animal studies have recently provided strong evidence for involvement of the endocannabinoid (eCB) system in memory function. Neuropsychological studies in humans have shown less convincing evidence but suggest that administration of cannabinoid substances affects encoding rather than recall of information. In this study, we examined the effects of perturbation of the eCB system on memory function during both encoding and recall. We performed a pharmacological MRI study with a placebo-controlled, crossover design, investigating the effects of Δ9-tetrahydrocannabinol (THC) inhalation on associative memory-related brain function in 13 …
Trauma Severity And Defensive Emotion-Regulation Reactions As Predictors Of Forgetting Childhood Trauma, Bette L. Bottoms, Cynthia J. Najdowski, Michelle A. Epstein, Matthew J. Badanek
Trauma Severity And Defensive Emotion-Regulation Reactions As Predictors Of Forgetting Childhood Trauma, Bette L. Bottoms, Cynthia J. Najdowski, Michelle A. Epstein, Matthew J. Badanek
Psychology Faculty Scholarship
Using a retrospective survey, we studied a sample of 1679 college women to determine whether reports of prior forgetting of sexual abuse, physical abuse, and other traumas could be explained by trauma severity and individual differences in the use of defensive emotion-regulation reactions (i.e., repressive coping, dissociation, and fantasy proneness). Among victims of physical abuse (but not sexual abuse or other types of trauma), those who experienced severe abuse and used defensive reactions were sometimes more likely to report temporary forgetting of abuse, but other times less likely to report forgetting. We also found unanticipated main effects of trauma severity …
Dynamic Aspects Of Musical Imagery, Andrea R. Halpern
Dynamic Aspects Of Musical Imagery, Andrea R. Halpern
Faculty Conference Papers and Presentations
Auditory imagery can represent many aspects of music, such as the starting pitches of a tune or the instrument that typically plays it. In this paper, I concentrate on more dynamic, or time-sensitive aspects of musical imagery, as demonstrated in two recently published studies. The first was a behavioral study that examined the ability to make emotional judgments about both heard and imagined music in real time. The second was a neuroimaging study on the neural correlates of anticipating an upcoming tune, after hearing a cue tune. That study found activation of several sequence-learning brain areas, some of which varied …
Semantic Priming Of Familiar Songs, Sarah K. Johnson, Andrea R. Halpern
Semantic Priming Of Familiar Songs, Sarah K. Johnson, Andrea R. Halpern
Faculty Journal Articles
We explored the functional organization of semantic memory for music by comparing priming across familiar songs both within modalities (Experiment 1, tune to tune; Experiment 3, category label to lyrics) and across modalities (Experiment 2, category label to tune; Experiment 4, tune to lyrics). Participants judged whether or not the target tune or lyrics were real (akin to lexical decision tasks). We found significant priming, analogous to linguistic associative-priming effects, in reaction times for related primes as compared to unrelated primes, but primarily for within-modality comparisons. Reaction times to tunes (e.g., "Silent Night") were faster following related tunes ("Deck the …
Introduction To The Neurosciences And Music Iv: Learning And Memory, Andrea R. Halpern
Introduction To The Neurosciences And Music Iv: Learning And Memory, Andrea R. Halpern
Faculty Conference Papers and Presentations
The conference entitled "The Neurosciences and Music-IV: Learning and Memory" was held at the University of Edinburgh from June 9-12, 2011, jointly hosted by the Mariani Foundation and the Institute for Music in Human and Social Development, and involving nearly 500 international delegates. Two opening workshops, three large and vibrant poster sessions, and nine invited symposia introduced a diverse range of recent research findings and discussed current research directions. Here, the proceedings are introduced by the workshop and symposia leaders on topics including working with children, rhythm perception, language processing, cultural learning, memory, musical imagery, neural plasticity, stroke rehabilitation, autism, …