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Effects Of Traumatic Brain Injury On Pediatric Brain Volume, Sanam Jivani Lalani
Effects Of Traumatic Brain Injury On Pediatric Brain Volume, Sanam Jivani Lalani
Theses and Dissertations
This study investigated the effects of lesion presence within larger brain networks (e.g., default mode network (DMN), salience network (SN), and mentalizing network (MN)) in the chronic phase of a pediatric traumatic brain injury (TBI) and the effect on social function. We compared children with a TBI to children with an orthopedic injury (OI) with three different aims. The first aim was to determine whether network volume differed by group (e.g., TBI vs. OI). Second, investigate if lesion presence in a sub component region of the network resulted in total network volume loss for that network. Finally, learn whether network …
Cognition And Behavioral Outcome In Children And Adolescents With Previous Ecmo Treatment: A Case Series With Neuroimaging Correlates, Juliann Thompson
Cognition And Behavioral Outcome In Children And Adolescents With Previous Ecmo Treatment: A Case Series With Neuroimaging Correlates, Juliann Thompson
Theses and Dissertations
Extra-corporeal membrane oxygenation (ECMO) is a life-saving procedure for patients in respiratory or cardiac distress. Prior studies have demonstrated several known risks to the procedure, such as hypoxia, stroke, and other neurological complications (Cheng et al., 2014) that can lead to temporary or permanent deficits in motor abilities, developmental trajectory, academic abilities, and cognition (Glass et al., 1995). Although several studies have investigated morbidity and mortality rates of pediatric ECMO patients, few have looked at cognitive deficits, and even fewer at magnetic resonance imaging in relation to neuropsychological outcome and behavioral, emotional, or social functioning. The aims of this study …
A Comparison Of Qualitative And Quantitative White Matter Methods In Pediatric Traumatic Brain Injury, Kacie Larae Wright
A Comparison Of Qualitative And Quantitative White Matter Methods In Pediatric Traumatic Brain Injury, Kacie Larae Wright
Theses and Dissertations
Magnetic resonance imaging is used to assess white matter (WM) abnormalities including total WM volumes and WM hyperintensities (WMHs). Comparisons between several qualitative and quantitative methods to assess WM that are used in research and clinical settings are lacking in pediatric traumatic brain injury (TBI). This study 1) WM methods including Scheltens ratings, manual tracings, NeuroQuant®, and FreeSurfer; (2) compared total WM volumes and WMHs to assess potentially similar reporting of WM integrity; and (3) assessed the relationship between cognitive functions (intelligence, attention, processing speed, and language) and WM in pediatric TBI.Sixty participants (65% male) between ages 8-13 years old, …
Psychiatric Symptom Severity Following Pediatric Traumatic Brain Injury: A Meta-Analysis, Benjamin Douglas Eschler
Psychiatric Symptom Severity Following Pediatric Traumatic Brain Injury: A Meta-Analysis, Benjamin Douglas Eschler
Theses and Dissertations
Objectives: A meta-analysis was conducted to determine the average effect size of internalizing and externalizing symptoms after pediatric traumatic brain injury across a range of severity (mild, moderate, and severe). Two-meta-regressions were also conducted to determine the role of age at injury at time since injury on these effect sizes.Participants and Methods: 9725 titles and abstracts were collected from PubMed, PsycInfo, and Web of Science. Of these, 63 full-text articles were examined for inclusion criteria to determine eligibility for the study. To be included, the studies needed to be published prior to March 2017 in English, needed to have a …
Psychiatric Symptom Severity Following Pediatric Traumatic Brain Injury: A Meta-Analysis, Benjamin Douglas Eschler
Psychiatric Symptom Severity Following Pediatric Traumatic Brain Injury: A Meta-Analysis, Benjamin Douglas Eschler
Theses and Dissertations
Objectives: A meta-analysis was conducted to determine the average effect size of internalizing and externalizing symptoms after pediatric traumatic brain injury across a range of severity (mild, moderate, and severe). Two-meta-regressions were also conducted to determine the role of age at injury at time since injury on these effect sizes.Participants and Methods: 9725 titles and abstracts were collected from PubMed, PsycInfo, and Web of Science. Of these, 63 full-text articles were examined for inclusion criteria to determine eligibility for the study. To be included, the studies needed to be published prior to March 2017 in English, needed to have a …