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Legacy Theses & Dissertations (2009 - 2024)

Theses/Dissertations

2019

Ayahuasca

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Assessing Novel Expectancies About Ayahuasca : A Preliminary Report, Brianna Rose Altman Jan 2019

Assessing Novel Expectancies About Ayahuasca : A Preliminary Report, Brianna Rose Altman

Legacy Theses & Dissertations (2009 - 2024)

Given the growing popularity of Ayahuasca, we sought to identify why people might use this psychoactive brew rather than classic hallucinogens like LSD or psilocybin. Experienced users (N=139) completed an online survey about their use of hallucinogens, including ayahuasca, how their ayahuasca experiences differed from those with other hallucinogens, and their willingness to use ayahuasca over other hallucinogens in the future. Participants reported meaningful differences between ayahuasca and other hallucinogens, which apparently related to positive connections to nature and other people, dramatic or terrifying negative thoughts, and aversive physical reactions. Multiple measures of self-reported likelihood of using ayahuasca again increased …


Ayahuasca's Antidepressant Effects Covary With Behavioral Activation As Well As Mindfulness, Maha N. Mian Jan 2019

Ayahuasca's Antidepressant Effects Covary With Behavioral Activation As Well As Mindfulness, Maha N. Mian

Legacy Theses & Dissertations (2009 - 2024)

Ayahuasca, a plant-based hallucinogen that serves as a spiritual medicine in South America, has improved depression in at least one placebo-controlled clinical trial. Case studies suggest that dramatic behavioral changes often follow the Ayahuasca ceremony, but most explanations of antidepressant effects focus on observed changes in mindfulness. The present study investigated if both mindfulness and behavioral activation might also contribute to these anti-depressant effects. We surveyed individuals (N = 152) about their changes in depressive symptoms, Behavioral Activation, and mindfulness after an Ayahuasca experience. Mindfulness was strongly associated with reduced depression severity (r = -.670, p < .001), while behavioral activation was moderately linked (r = -.474, p < .001). Changes in depressive symptoms (Center for Epidemiological Sciences Depression Short Form [CES-D-10]) covaried with subscales from the Five Facet Mindfulness Questionnaire [FFMQ] and Experiences Questionnaire [EQ], confirming previous findings (beta = -.57, [95% CI (- 5.70) - (- 3.25)], p < .001). In addition, a modification of the Behavioral Activation for Depression Scale-Short Form [BADS-SF] accounted for significant unique variance in the improvements in depression (beta = -.16, [95% CI (-6.32) - (-0.08)], p < .05). These results suggest that changes in behavioral activation likely serve as an important mechanism underlying Ayahuasca’s antidepressant effects. Future clinical trials could benefit from tracking behavioral activation. In addition, a concerted focus on increasing valued, positive activities might enhance Ayahuasca’s anti-depressant effects.