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Serotonin And Stress Responding In Animals: Role Of 5-Ht.2a/C Receptors In The Central And Peripheral Nervous Systems, Sarah Mathews Uzelac
Serotonin And Stress Responding In Animals: Role Of 5-Ht.2a/C Receptors In The Central And Peripheral Nervous Systems, Sarah Mathews Uzelac
LSU Doctoral Dissertations
Behavioral responses to stressors can be influenced in different ways by both serotonin (5-HT) agonists and antagonists. Further study, of both different stressors as well as different 5-HT agents, is needed to clarify the place of 5-HT in stress responding. To date, no published report has investigated the influence of centrally and/or peripherally administered 5-HT2A/C agonist DOI or the 5-HT2A/C antagonist ketanserin on behaviors evoked by tail pinch or open field stressors. Five separate, related experiments were conducted to investigate this influence. It was hypothesized that that peripherally (Experiment 1), centrally (Experiment 2), and centrally + peripherally (Experiment 3) injected …
Effects Of 5-Ht2 Receptor Ligands On Tail Pinch-Induced Stress Responding And Open Field Behavior, John K. Hearn
Effects Of 5-Ht2 Receptor Ligands On Tail Pinch-Induced Stress Responding And Open Field Behavior, John K. Hearn
LSU Master's Theses
Stress is known to exert an influence on neuroendocrine, autonomic, hormonal, and immune functioning. As a result of the debilitating effects of stress on numerous bodily systems, there exists a large body of research devoted to the etiology, physiological sequelae, and treatment of the condition. Further, the neurotransmitter serotonin (5-HT) has been implicated in stress responding. Presently, there is conflict in the literature as to the precise role serotonin plays in mediating the stress response. This study was an attempt to further elucidate the role of 5-HT in mediating an organism’s response to tail pinch stress and the open field. …