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An In Vitro Model Of Ovarian Cancer: Studying The Effects Of Talc And Pycnogenol®, Amber Renée Buz'zard

Loma Linda University Electronic Theses, Dissertations & Projects

Ovarian cancer is the sixth most common cancer and accounts for more deaths than any other cancer of the female reproductive system. The American Cancer Society has suggested that poor diet, talc and industrial pollutants may increase the risk of developing ovarian cancer. Talc is ubiquitous and concern is raised about its safety, role as a possible carcinogen and known ability to cause irritation and inflammation. Due to the silent nature of ovarian cancer, chemoprevention is a high priority. The most useful chemopreventive compounds will inhibit, delay or reverse carcinogenesis, and can be taken for long periods of time with …

Determinants Of Long-Term Care Service Utilization By Mexican-American Family Caregivers, Angelica P. Herrera

Loma Linda University Electronic Theses, Dissertations & Projects

Objectives: Participation in long-term care services may prevent the deterioration of family caregivers' mental and physical health, yet research suggests that Latino caregivers may forego using long-term care services in the absence of other barriers to long-term care use (e.g., lack of insurance).

Methods: An adapted version of the Andersen Model of Health Care Service Utilization served as a framework for examining familism, acculturation, gender roles, religiosity, and knowledge and perceptions about long-term care, as potential determinants of long-term care service use, alongside other factors known for their association with long-term care use (e.g. functional status of care recipient, caregiver …

Using The Outcome Questionnaire 45.2 In Obesity Treatment, Adam L. Arechiga

Loma Linda University Electronic Theses, Dissertations & Projects

Purpose: The purpose of this study was to determine if the Outcome Questionnaire 45.2 (OQ-45) can be used in the treatment of obesity to predict participant dropout and initial treatment success, in terms of weight loss (Lambert et. al, 2002a). The OQ-45 has been used with success to predict dropout from psychotherapy in clinical populations. It was hypothesized that higher pretreatment OQ-45 scores would be associated with less program completion and less weight loss by the end of treatment.

Method: The study employed a non-experimental time series design. Seventy-eight participants were recruited from the three local obesity treatment programs, which …

The Relationship Between High Sensitivity C-Reactive Protein, Metabolic Syndrome And Exercise, Micheline A. Vargas

Loma Linda University Electronic Theses, Dissertations & Projects

Background: It is well known that regular physical activity is associated with lower risk of chronic diseases such as diabetes and cardiovascular disease. Physical activity is also considered an important determinant of metabolic syndrome. All levels of metabolic syndrome, diabetes, and cardiovascular disease are thought to involve inflammation. Physical activity may reduce risk, at least in part, by modifying the inflammatory process. Recent studies have demonstrated an inverse relationship between inflammatory markers, such as high sensitivity C-reactive protein (hs-CRP), and physical activity. Elevated hs-CRP appears to be an independent predictor of both CVD and diabetes. Recent evidence also suggests that …

Low Birth Weight, Very Low Birth Weight And Infant Mortality In San Bernardino County : A Secondary Analysis Of Maternal Factors, Rebecca D. Nanyonjo

Loma Linda University Electronic Theses, Dissertations & Projects

Purpose: National and state infant mortality rates have slowly declined over the last several years. Despite this reduction, San Bernardino County still has one of the highest infant mortality rates in California and racial disparities between Black and White infants not only persist but continue to widen. These disparities remain at the forefront of concern. Healthy People 2010 target objectives have yet to be reached, while national and state proposed plans have supported the statement that a community's largest health problem is initiated by its infant mortality. The purpose of this study was to investigate maternal factors through use of …

Factors That Influence The Blood Flow Response Of Skin To Electrical Stimulation, Abdul-Majeed Raja Al-Malty

Loma Linda University Electronic Theses, Dissertations & Projects

Female reproductive hormones, aging, global heating and local heating are factors affecting skin blood flow (SBF), but their effect on electrical stimulation (ES) has never been examined until the present investigation. To investigate female reproductive hormones, nine women (age= 25.6±3.5 years) with a normal menstrual cycle (MC) underwent ES in thermoneutral (25°±0.5°C) and warm environments (35°±0.5°C). To investigate aging, ES was applied on active young (n=15, age=32.1±8.3 years) and old (n=8, 64.5±6.2 years) groups in thermoneutral and warm environments. To investigate the effect of global and local heating, groups of 15 and 18 subjects (age= 18-40 years) experienced ES under …

Pnes: Neuropsychological Impairments & Psychological Symptomatology, Adriana Macias

Loma Linda University Electronic Theses, Dissertations & Projects

The present study utilized a standardized neuropsychological evaluation and self report measures to compare 52 female patients, 18 years of age and older with a video-electroencephalogram (V-EEG) confirmed diagnosis of psychogenic non-epileptic seizures (PNES) (n₁=29) to a group of left temporal lobe epilepsy (L-TLE) demographically matched patients (n₂=23). In an attempt to overcome methodological confounds of previously reported studies, participants were chosen based on stringent exclusion criteria, which barred mixed etiologies. The purpose of this study was to investigate possible differences in neuropsychological functioning, mood, and personality characteristics between individuals with PNES and those with L-TLE. …