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Public Health

University of South Carolina

Asthma

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The Impact Of Meal Dietary Inflammatory Index On Exercise-Induced Changes In Airway Inflammation In Adults With Asthma, Katrina P. Mcdiarmid, Lisa G. Wood, John W. Upham, Lesley K. Macdonald-Wicks, Nitin Shivappa Mbbs, Mph, Ph.D., James R. Hébert Scd, Hayley A. Scott Oct 2022

The Impact Of Meal Dietary Inflammatory Index On Exercise-Induced Changes In Airway Inflammation In Adults With Asthma, Katrina P. Mcdiarmid, Lisa G. Wood, John W. Upham, Lesley K. Macdonald-Wicks, Nitin Shivappa Mbbs, Mph, Ph.D., James R. Hébert Scd, Hayley A. Scott

Faculty Publications

Research suggests exercise may reduce eosinophilic airway inflammation in adults with asthma. The Dietary Inflammatory Index (DII®) quantifies the inflammatory potential of the diet and has been associated with asthma outcomes. This study aimed to determine whether the DII of a meal consumed either before or after exercise influences exercise-induced changes in airway inflammation. A total of 56 adults with asthma were randomised to (1) 30–45 min moderate–vigorous exercise, or (2) a control group. Participants consumed self-selected meals, two hours pre- and two hours post-intervention. Energy-adjusted DII (E-DIITM) was determined for each meal, with meals then characterised as “anti-inflammatory” or …


Genetic And Epigenetic Variations In Asthma And Wheeze Illnesses, Todd M. Everson Dec 2015

Genetic And Epigenetic Variations In Asthma And Wheeze Illnesses, Todd M. Everson

Theses and Dissertations

Asthma, a chronic respiratory condition, is common worldwide with no cure and limited effective prevention strategies. It is well recognized that asthma has a multifaceted etiology, though many of the underlying mechanisms involved in asthma development, persistence and remission are still convoluted. Epigenetic mechanisms, such as DNA methylation, regulate gene-expression but are not related to changes in the actual DNA sequence. Recently, differential patterns of DNA methylation within many genes have been associated with asthma, particularly within genes involved in the differentiation of pro-inflammatory T-helper 2 (Th2) cells. DNA methylation patterns within less known biologic pathways undoubtedly are involved in …


Two Studies Of Family-Centered Care Family-Centered Care And Shared Decision Making: Are They The Same Construct? And The Association Of Family-Centered Care And Shared Decision Making With Receipt Of All Needed Prescription Drugs And Emergency Department Visits In Children With Asthma, Barbara Lee Brumbaugh Aug 2014

Two Studies Of Family-Centered Care Family-Centered Care And Shared Decision Making: Are They The Same Construct? And The Association Of Family-Centered Care And Shared Decision Making With Receipt Of All Needed Prescription Drugs And Emergency Department Visits In Children With Asthma, Barbara Lee Brumbaugh

Theses and Dissertations

Family-Centered Care (FCC) is considered the standard of care in pediatrics, being affirmed in 2003 by the American Academy of Pediatrics (AAP). Family centered practices center around five specific provider actions: (1) did the provider spend enough time; (2) did the provider listen carefully; (3) was the provider sensitive to the needs of the family, including their values and customs; (4) did the provider provide information as needed; (5) did the provider make the caregiver feel like a partner in the care of the child. In addition to FCC practices, shared decision making (SDM) has been indicated as important in …


Role Of Allergic Sensitization, Filaggrin Variants, And Dna, Ali H. Ziyab Aug 2014

Role Of Allergic Sensitization, Filaggrin Variants, And Dna, Ali H. Ziyab

Theses and Dissertations

Background: Allergic disorders, including eczema, asthma, and rhinitis, have emerged as a global public health concern due to their elevated prevalence and the associated clinical morbidity. Environmental, immunologic, and genetic factors have been implicated in the pathogenesis of allergic disorders. Allergic sensitization (representing deviated immune responses) and filaggrin gene (FLG) variants (leading to dysfunctional epidermal barrier) have shown to be common predisposing factors in the development of allergic disorders. However, there is a lack of knowledge on their joint effects on the development of single and multiple (coexistence) allergic disorders. More recently, epigenetic mechanisms, such as DNA methylation, have emerged …