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University of South Carolina

Theses and Dissertations

Theses/Dissertations

2017

Coastal Cohort

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Prenatal Methylmercury Exposure In A South Carolina Coastal Cohort, Alexis Donohue Jan 2017

Prenatal Methylmercury Exposure In A South Carolina Coastal Cohort, Alexis Donohue

Theses and Dissertations

Objectives: Methylmercury is a neurotoxin that has the ability to cross the placenta and adversely affect the developing fetus. Our primary objective was to investigate whether prenatal methylmercury exposure varied longitudinally, and whether differences were associated with maternal characteristics.

Methods: Pregnant mothers were recruited in Charleston, South Carolina (8-17 weeks gestation) (n=78). Blood samples were collected during both early (11.8 ± 1.7 weeks) and late (35.3 ± 2.0 weeks) gestation. Blood total mercury and methylmercury concentrations were analyzed. Upon enrollment in the study, mothers filled out a sociodemographic questionnaire that included questions regarding maternal age, race/ethnicity, and education level. Additionally, …