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Bayesian Methods; Ecological Bias; Ecological Correlation Studies; Hierarchical Models; Prior Distributions; Spatial Epidemiology; Standardization.
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Disease Mapping And Spatial Regression With Count Data, Jon Wakefield
Disease Mapping And Spatial Regression With Count Data, Jon Wakefield
UW Biostatistics Working Paper Series
In this paper we provide critical reviews of methods suggested for the analysis of aggregate count data in the context of disease mapping and spatial regression. We introduce a new method for picking prior distributions, and propose a number of refinements of previously-used models. We also consider ecological bias, mutual standardization, and choice of both spatial model and prior specification. We analyze male lip cancer incidence data collected in Scotland over the period 1975–1980, and outline a number of problems with previous analyses of these data. A number of recommendations are provided. In disease mapping studies, hierarchical models can provide …