Digital Commons Network^™

Oprm1 Genotype Interacts With Serotonin System Dysfunction To Predict Alcohol-Heightened Aggression In Primates, Carlos A. Driscoll, Stephen G. Lindell, Melanie L. Schwandt, Stephen J. Suomi, J. Dee Higley, Markus Heilig, Christina S. Barr

Faculty Publications

Although the notion that alcohol promotes violence is widespread, not all individuals are aggressive while intoxicated. Genetic variation could be a contributing factor to individual differences in alcohol-heightened aggression. The present study examines the effects of OPRM1C77G genotype on responses to threat in rhesus macaques under normal conditions and following alcohol administration. Prior studies have shown that a low CSF level of 5-HIAA is a trait marker for individuals prone to escalated aggression. We wanted to examine whether the predictive value for this marker on aggression was moderated by OPRM1 genotype. Animals were administered alcohol (BAC 100-200 mg%), were provoked …

Toxoplasma Gondii Seropositivity And Substance Use In Us Adults, Bruce L. Brown, Andrew N. Berrett, Shawn D. Gale, Lance D. Erickson, Evan L. Thacker, Dawson W. Hedges

Faculty Publications

The intracellular parasite Toxoplasma gondii (Nicolle et Manceaux, 1908) infects humans resulting in acute toxoplasmosis, an infection that in immunocompetent people is typically mild but results in persistent latent toxoplasmosis. In that T. gondii appears to affect dopamine synthesis and because addicting drugs affect midbrain dopamine transmission, latent toxoplasmosis could influence substance use. Using both the third and continuous National Health and Nutrition Examination Surveys from the US Centers for Disease Control and Prevention, we used logistic regression to test for associations between T. gondii seropositivity and subject self-report of having ever used tobacco, alcohol, marijuana, cocaine, heroin, or methamphetamine. …

Evaluation Of Neurobiological Risk Factors For Alcohol Consumption; Convergent Evidence For Predispositional Effects Of Brain Volume, David Baranger

Arts & Sciences Electronic Theses and Dissertations

Alcohol is one of the most widely used psychoactive substances and accounts for 5% of global disease burden. The goal of the present work is to help advance efforts to both identify prognostic markers of risk, and to understand the mechanisms by which alcohol consumption impacts health. Early life stress is one of the strongest predictors of mental illness, including alcohol dependence, and has been hypothesized to impact risk via modulation of striatal reward functions and reward learning. Studies examined the effect of stress on reward learning and processing, and tested for moderation by genetic and environmental risk. Results were …

Baked And Buzzed: Investigating The Influence Of Co-Use Of Cannabis And Alcohol On White Matter Integrity In Emerging Adults, Natasha E. Wright

Theses and Dissertations

Objective: Growing evidence suggests alcohol and cannabis use independently alter neural structure and functioning, particularly during sensitive developmental time periods such as adolescence and emerging adulthood. However, there has been minimal investigation into the effects co-occurring use of these two substances, despite preliminary evidence of unique acute and psychopharmacological changes due to using alcohol and cannabis together.

Method: Data drawn from the IDEAA Consortium was utilized to assess white matter integrity as measured by FreeSurfer’s TRACULA in emerging adults (n=192; 16-27 years old). Timeline Follow-Back was used to calculate past month cannabis use, alcohol use, co-use days, binge alcohol episode, …

Women's Response Performance In Sexually Risky Situations: Associations With Sexual Victimization History, Alcohol Use, Psychopathology, And Sexual Attitudes, Kristen N. Vitek

Psychology ETDs

This study evaluated the effects of sexual victimization history, alcohol use, psychopathology, and sexual attitudes on the effectiveness of women’s response performance in hypothetical social situations depicting risk for sexual victimization. Two hundred and fifty undergraduate women first listened to audiotaped descriptions of the hypothetical social situations. They then were given a response to each situation deemed in prior work by experts in the sexual victimization field to be effective at reducing victimization risk and asked to provide each response verbally while they were being videotaped. Participants then completed measures assessing prior victimization history, alcohol use, psychopathology, and sexual attitudes. …

Evaluating Differences In Drink Refusal Training And Posttreatment Outcomes In Women In Individual Alcohol Treatment, Rosa Munoz

Psychology ETDs

This study sought to establish the topography of drink refusal behaviors clients engage in while undergoing manual-guided Cognitive Behavioral Therapy (CBT) for Alcohol Use Disorders (AUD). Prior research has demonstrated that clients who receive specific skills training on how to assertively refuse drinks are less likely to relapse. Behavioral coding has been used previously to explore in-session behaviors by both client and therapist. Using this methodology, a coding manual (Drink Refusal and Motivation-Alcohol; DRAM-A) was developed for the present study. We sought to explore the relationship between differential types of drink refusal behaviors uttered by clients receiving treatment for AUD …

A Field Study Examining The Effect Of High Intoxication Levels And Identification Format On Witnesses' Memory For Faces And Events, Christopher Altman

FIU Electronic Theses and Dissertations

Members of the legal system (e.g., experts, jurors, investigators) are often skeptical of the information provided by intoxicated witnesses given the negative stigma surrounding alcohol and memory. However, studies examining the relationship between alcohol and witness memory often find that alcohol has no effect on peoples’ recall or their ability to identify a previously seen face. While insightful, the validity of these findings has been questioned given the low-moderate blood alcohol concentration (BAC) levels tested in these predominantly laboratory-based studies, which may not be high enough to consistently expose the cognitive deficits alcohol is expected to create. The present study …

Cross-Cutting Mechanisms That Contribute To Developing Anxiety-Related Alcohol Use Problems Among College Students, Vincenzo Roma

Department of Psychology: Dissertations, Theses, and Student Research

Drinking behaviors among college students have become problematic as evidenced by 20% of students who endorse five or more problems associated with alcohol use. Alcohol use problems are associated with numerous anxiety problems and can begin as early as young adolescence. The period for risk of developing emotional problems peaks during the transition to college. Despite the relationship between anxiety and alcohol use problems, little is known about the cross-cutting mechanisms that explain their relationship and comorbidity. Researchers have proposed affective (i.e. anxiety sensitivity and distress tolerance) and alcohol-specific motivations (i.e. expectancies, valuations, peer influence, and drinking motives) as vulnerabilities …

Snapchat And Its Relationship To Alcohol Consumption And Associated Behaviours, Kellie S. Thomas

Undergraduate Honours Theses

The current study examined the relationship between Snapchat use, alcohol consumption and associated behaviours and motivations. The participants in the study were 200 undergraduate students enrolled at Western University. Participants in the control condition watched a video made up of 11 Snapchats where subjects were consuming water, the experimental condition was identical except subjects were consuming alcoholic beverages. Regression analyses indicated that relationship management motivation (RMM) and self-enhancement motivation (SEM) were the most significant predictors across condition and gender. Implications are discussed.

The Effects Of Alcohol Priming And Alcohol-Related Cues On Subsequent Alcohol Preferences, Kathleen R. Owens

Masters Theses, 2010-2019

The purpose of the current study was to investigate the effects of alcohol priming and alcohol-related cues on subsequent alcohol preferences. Researchers assigned randomly 35 university students to 1 of 3 conditions: alcohol delivered in a red disposable plastic cup (AC; alcohol cue; n = 12), alcohol delivered in a cafeteria cup (AN; neutral cue; n = 11), or alcohol placebo (P; n = 12) delivered in a red disposable plastic cup. Participants consumed their assigned beverages, and then completed the Multiple Choice Procedure (MCP), a procedure that allows participants to make discrete choices between a standard alcoholic beverage and …

Interactions In Social Settings: The Relationship Between Alcohol And Sexual Assault Among College Students, Heather Lepper

MSU Graduate Theses

Research has linked alcohol to violence and sexual assault, especially within the college student population. Most of this research focuses on the effects of alcohol on victims or perpetrators of sexual assault and not on bystanders of such situations. This study examines how self-reported drinking behavior affects students' ability to recognize risk of sexual assault in written scenarios and the various barriers that would inhibit their willingness to intervene. A sample of 275 students (183 female, 92 male) were asked to read one of three scenarios and respond to a brief questionnaire adapted from Burn's (2009) Barriers to Bystander Intervention …

The Prospective Influence Of Religiousness On Alcohol Use: What Role Do Perceived Norms Play?, Corey Todd Brawner

Dissertations

Alcohol misuse is recognized as one of the most pressing health hazards for college students. Previous research has supported a protective relationship between religiousness and problematic alcohol use, but it is less clear what aspects of religiousness are protective and through what mechanisms its effect is exerted. The current study utilized a prospective design to accomplish three primary goals: (1) Delineate the protective effects of religious motivation and public participation on alcohol use and alcohol-related problems in a sample of undergraduates at a large public university in the southeastern United States, (2) determine whether effects were maintained long-term, and (3) …

The Moderating Role Of Pbs In The Relationship Between Positive Expectancies And Alcohol-Related Negative Consequences, Kray Scully

Master's Theses

Hazardous drinking college students have become an increasingly focused upon group within alcohol research, especially considering the extent of negative consequences they experience. Recently, increased positive expectancies has been identified as an influential contributor to increased hazardous drinking and alcohol-related negative consequences. However, more comprehensive evaluation of the domains of positive expectancies (e.g., sociability, tension reduction, sexual enhancement, liquid courage) is warranted to ascertain which types are more salient in predicting hazardous drinking and alcohol-related negative consequences. Further, research has yet to explore how protective behavioral strategies (PBS) affect the strength of the associations between specific positive expectancies and alcohol-related …

Effects Of Exposure To Alcohol-Related Cues On Racial Discrimination, Elena V. Stepanova, Bruce D. Bartholow, J. Scott Saults, Ronald S. Friedman

Faculty Publications

Prior research has shown that exposure to alcohol‐related images exacerbates expression of implicit racial biases, and that brief exposure to alcohol‐related words increases aggressive responses. However, the potential for alcohol cue exposure to elicit differential aggression against a Black (outgroup) relative to a White (ingroup) target—that is, racial discrimination—has never been investigated. Here, we found that White participants (N = 92) exposed to alcohol‐related words made harsher judgments of a Black experimenter who had frustrated them than participants who were exposed to nonalcohol words. These findings suggest that exposure to alcohol cues increases discriminatory behaviors toward Blacks.

Examination Of Approach And Avoidance Inclinations On The Reinforcing Value Of Alcohol, Emily T. Noyes, Robert C. Schlauch

Psychology Faculty Publications

Although behavioral economics tends to focus on environmental factors (i.e., price, availability) that act to influence valuation of alcohol, recent research has begun to address how motivational and cognitive factors influence an individual's demand for alcohol. Motivational states, including craving, are one possible mechanism underlying the value based decision making that demand represents. Using a multidimensional model of craving (Ambivalence Model of Craving), the current study examined the relationships between indices of alcohol demand (i.e., reinforcing value of alcohol) and craving (i.e., approach inclinations), and the ways in which competing desires moderate that relationship (i.e., avoidance inclinations). Individuals who reported …

Effects Of Exposure To Alcohol-Related Cues On Racial Prejudice, Elena V. Stepanova, Bruce D. Bartholow, J. Scott Saults, Ronald S. Friedman, Jinhao Chi, Abigail M. Hollis

Faculty Publications

Prior research (Stepanova, Bartholow, Saults, & Friedman, 2012) indicates that exposure to alcohol-related cues increases expressions of racial biases. This study investigated whether such effects can be replicated with other tasks assessing racial bias and whether they stem from stereotyping or prejudice. In two experiments participants (N₁ = 118; N₂ = 152) were exposed to either alcohol-related or neutral advertisements, and then completed a race-priming lexical decision task (LDT, Wittenbrink, Judd, and Park, 1997). Experiment 1 provided weak evidence that exposure to alcohol cues decreases positive attitudes toward Blacks, which was not confirmed in a high-powered replication …

University Students' Willingness To Assist Fellow Students Who Experience Alcohol-Related Facial Flushing To Reduce Their Drinking, Lanyan Ding, Lok-Wa Yuen, Ian M. Newman, Duane F. Shell

Department of Educational Psychology: Faculty Publications

This study explored bystanders’ willingness to help a friend who flushes when drinking to reduce his/her drinking. Alcohol-related facial flushing is an indicator of an inherited variant enzyme, aldehyde dehydrogenase (ALDH), that impairs alcohol metabolism and increases drinkers’ lifetime risk of certain aerodigestive cancers. Individuals who flush should reduce their alcohol exposure, but they may continue to drink if social pressures and rules of etiquette make not drinking socially risky. The analysis used data from 2912 undergraduate students from 13 universities in southwestern, central and northeastern China from a survey asking how they respond to someone’s flushing in various scenarios. …

Not All Fun And Games: Sexism And College Women's Alcohol Consumption, Hannah R. Hamilton

Dissertations

Previous research has suggested that racial discrimination (Pascoe & Smart Richman, 2009) and sexist experiences (Zucker & Landry, 2007) are related to increased alcohol consumption. However, ambivalent sexism theory suggests that there are two forms of sexism (Glick & Fiske, 1996; 1997). While hostile sexism refers to overtly negative attitudes towards women, benevolent sexism refers to positively valenced attitudes towards women that still serve to reaffirm masculine dominance. Therefore, the current studies explore the differential effects of experiencing hostile vs. benevolent sexism on college women's alcohol consumption using correlational (Study 1) and quasi-experimental (Study 2) methodologies. In addition, the current …

Social Isolation Predicting Problematic Alcohol Use In Emerging Adults: Examining The Unique Role Of Existential Isolation, Geneva Carolyn Yawger

Graduate College Dissertations and Theses

Current rates of excessive alcohol use and abuse among young adults are recognized as a major problem by scholars across a wide variety of fields. Here, I take a social psychological approach to understanding why individuals drink to excess, examining the unique role that a specific form of social isolation called existential isolation (feeling alone in one’s experiences of the world; Yalom, 1980; Pinel, Long, Murdoch, & Helm, 2017) may play in predicting alcohol use and abuse. The relationship between existential isolation and alcohol use is explored using both correlational and cross-lagged designs. Results indicate that existential isolation predicts alcohol …

University Students’Willingness To Assist Fellow Students Who Experience Alcohol-Related Facial Flushing To Reduce Their Drinking, Lanyan Ding, Lok-Wa Yuen, Ian M. Newman, Duane F. Shell

Department of Educational Psychology: Faculty Publications

This study explored bystanders’ willingness to help a friend who flushes when drinking to reduce his/her drinking. Alcohol-related facial flushing is an indicator of an inherited variant enzyme, aldehyde dehydrogenase (ALDH), that impairs alcohol metabolism and increases drinkers’ lifetime risk of certain aerodigestive cancers. Individuals who flush should reduce their alcohol exposure, but they may continue to drink if social pressures and rules of etiquette make not drinking socially risky. The analysis used data from 2912 undergraduate students from 13 universities in southwestern, central and northeastern China from a survey asking how they respond to someone’s flushing in various scenarios. …

A Psychometric Evaluation Of The Treatment Self-Regulation Questionnaire (Tsrq) For Assessing Motivations For Responsible Drinking, Dylan Keith Richards

Open Access Theses & Dissertations

Self-determination theory (SDT) may be useful for understanding alcohol use and alcohol-related consequences among college students. A version of the Treatment Self-Regulation Questionnaire (TSRQ; Ryan & Connell, 1989) exists for assessing motivations proposed by SDT for responsible drinking, but no study has evaluated its psychometric properties. Thus, the purpose of the present studies was to provide a psychometric evaluation of this version of the TSRQ. In Study 1, among a convenience sample of college student drinkers (n = 308), a four-factor structure of the TSRQ that is theoretically consistent with SDT was supported; however, the amotivation subscale demonstrated unacceptable internal …

Factors That Influence The Perceived Risk Of Driving Under The Influence Of Small Amounts Of Marijuana And Alcohol (Dui-Sama), Gabriel Andrew Frietze

Open Access Theses & Dissertations

The national trend toward the legalization of recreational marijuana use will likely increase the number of opportunities for young adults to legally drive under the combined influence of small amounts of marijuana and alcohol (DUI-SAMA). Research suggests that driving performance is moderately impaired when small amounts of marijuana and alcohol are consumed independently; however, driving performance is dramatically impaired when both substances are consumed in combination. The present study investigated the perceived risk of DUI-SAMA under two levels of stress (no stress, stress) and three levels of urgency (non-urgent, semi-urgent, urgent). One-hundred and sixty-five marijuana users (Mage = 20.3) were …

The Effect Of Laboratory Manipulations Of Negative Affect On Alcohol Craving And Use: A Meta-Analysis, Konrad Bresin, Yara Mekawi, Edelyn Verona

Psychology Faculty Publications

Scientific and lay theories propose that negative affect plays a causal role in problematic alcohol use. Despite this common belief, supporting experimental evidence has been mixed. Thus, the goals of this study were to (a) meta-analytically quantify the degree to which experimentally manipulated negative affect influenced alcohol use and craving in the laboratory, (b) examine whether the size of this effect depended on key manipulation characteristics (i.e., self-relevance of the stressor, timing of the end of the stressor, and strength of negative affect induction) or sample characteristics (i.e., substance use history). Across 41 studies (N = 2,403), we found …

A Deviance Regulation Theory Intervention To Reduce Alcohol Problems Among First-Year College Students, Angelina V. Leary

Honors Undergraduate Theses

OBJECTIVE: An alcohol-drinking culture exists among first-time-in-college students, where many of these students come to their university relatively inexperienced with alcohol, which may increase alcohol-related consequences. Several interventions exist to combat this campus problem. The current study investigates the use of a Deviance Regulation Theory (DRT) intervention, presented in a web-based manner, to increase alcohol Protective Behavioral Strategies (PBS), such as monitoring drinks, using a designated driver, and drinking water in between alcoholic beverages, among college freshmen. METHOD: College freshmen participants (N = 157) completed web-based surveys examining alcohol behaviors once a week for six weeks. Participants were randomly …

College Student Alcohol Use And Engagement In Prevention Programming, Alexis H. Branch, Shimona Kumar, Christina Mcgrath

Undergraduate Research Posters

Social problems and adverse consequences have been associated with risky alcohol use (Paschall et al, 2015). Personalized Normative Feedback (PNF) has been utilized to address these problems (White and Hingson, 2014) by comparing students’ alcohol use to campus or national norms (Butler et al, 2009). The current investigation sought to understand differences in alcohol use behaviors in freshmen who did and did not report completion of a personalized feedback intervention (PFI) in a diverse sample of college students from the Spit for Science (S4S) project. S4S is a campus-wide, longitudinal study on the genetic and environmental factors that contribute to …

Quantitative Assessment Of Psycho-Social Factors Associated With Alcoholics Anonymous Involvement, Dianne Bentley

Walden Dissertations and Doctoral Studies

Alcohol use disorders are a major health problem in the United States; approximately 7.4% of the population meets the criteria for alcohol abuse or dependence. However, Reed, Levin, and Evans (2012) reported a lack in research regarding alcoholism's risk factors and how these influence Alcoholics Anonymous involvement. Though there is evidence for several risk factors, researchers have found mixed results regarding gender and impulsivity. Social learning theory was the theoretical foundation of this study and guided the exploration and interpretation of these risk factors. Therefore, the purpose of this quantitative, nonexperimental study was to understand the relationship that impulsivity (as …

Alcohol-Induced Impairment Of Simulated Driving Performance And Behavioral Impulsivity In Dui Offenders, Nicholas A. Van Dyke

Theses and Dissertations--Psychology

Licensed drivers arrested for driving under the influence (DUI) of alcohol have increased rates of vehicle crashes, moving violations, traffic tickets, and contribute to an estimated 120 million occurrences of impaired driving per year (Evans, 2004; Jewett et al., 2015). Survey research on DUI offenders indicates traits of impulsivity (e.g., sensation seeking). Together, these pieces of evidence suggest that DUI offenders display patterns of impulsive action and risk-taking while driving. However, to-date DUI offenders are rarely studied in a laboratory setting, and not much is known about how they respond to a dose of alcohol. The present study examined the …

The Effects Of Risky Alcohol Use And Type Of Hook Up Behaviors On The Relationship Between Hooking Up To Cope And Negative Affect, Leah E. Stevens

Psychology Theses & Dissertations

Hook up behaviors are sexual behaviors that participants engage in consensually without the expectation of a romantic commitment, and occur frequently in the college context and often co-occur with binge drinking. Research indicates several factors (i.e., alcohol intoxication, type of sexual behavior, specific motives for hooking up, gender) are predictors of negative emotions associated with hook up experiences, such as regret, shame, confusion, and disappointment. Using hooking up as a coping mechanism coupled with experiencing negative emotions due to hook up experiences are associated with aspects of poor mental health such as depression and anxiety. Therefore, the present sought: (1) …