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Apolipoprotein Status And Cognitive Functioning In Adulthood: Role Of Physical Health And Social Network Characteristics, Jennifer Lee Silva
Apolipoprotein Status And Cognitive Functioning In Adulthood: Role Of Physical Health And Social Network Characteristics, Jennifer Lee Silva
LSU Doctoral Dissertations
This study examined the relationships among cognitive function, physical health, social network characteristics, and apolipoprotein (APOE) genotype in participants from the Louisiana Healthy Aging Study. Prior literature has shown that the ε4 allele of APOE is associated with cognitive deficits (Wisdom, Callahan, & Hawkins, 2009). This study failed to find any relation between APOE genotype (ε4 carrier vs. non-carrier) and cognitive ability after controlling for age and education level. Tests for physical health mediation and social network moderation did not alter the ε4/cognition null results. This finding conflicts with prior research suggesting that physical activity and health modify the association …