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The Cortisol/Dhea Ratio And Sexual Function In Women With And Without A History Of Depression, Carolyn Marie Dundon
The Cortisol/Dhea Ratio And Sexual Function In Women With And Without A History Of Depression, Carolyn Marie Dundon
Graduate College Dissertations and Theses
The comorbidity between female sexual dysfunction (FSD) and major depressive disorder (MDD) is well documented; however, the mechanism(s) underlying the relationship between these disorders has not been defined. The literature has associated the adrenal hormones cortisol and dehydroepiandrosterone (DHEA) with FSD and MDD, suggesting a biological mechanism that may elucidate the comorbidity between these disorders. Based on evidence pointing to a high cortisol/DHEA ratio (C/D Ratio) in MDD and low DHEA in FSD, this study investigated if the potential association between a high C/D Ratio and FSD would be greater for women with a history of MDD when compared to …