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Cognitive Control Disruption And Quality Of Life In Individuals With Obsessive-Compulsive Disorder, Isaac J. Hunt

Theses and Dissertations

Obsessive-compulsive disorder (OCD) is associated with diminished quality of life and cognitive control dysfunction. Conflict adaptation is a reflection of cognitive control, and consists of the ability to detect conflict in previous trials and adjust performance on current trials. Conflict adaptation is thought to rely on interplay between the anterior cingulate cortex (ACC) and dorsolateral prefrontal cortex (dlPFC) for detecting conflict and signaling for increases in control, respectively. We hypothesized that individuals with OCD would show reduced conflict adaptation effects in response times, error rates, ACC activation, and dlPFC activation when compared with healthy control subjects. We also expected diminished …