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Atypical Language Lateralization In Epilepsy Patients, Gabriel Möddel, Tara T. Lineweaver, Stephan U. Schuele, Julia Reinholz, T. Loddenkemper
Atypical Language Lateralization In Epilepsy Patients, Gabriel Möddel, Tara T. Lineweaver, Stephan U. Schuele, Julia Reinholz, T. Loddenkemper
Scholarship and Professional Work - LAS
Purpose: To investigate whether atypical language dominance in epilepsy patients is related to localization and type of lesions.
Methods: Four hundred and forty-five epilepsy patients received bilateral Wada testing. Language was classified as left (L), right (R), bilateral-dependent (BD, speech arrest after left and right injections), or bilateral-independent (BI, no speech arrest after either injection). Groups were compared regarding handedness and magnetic resonance imaging (MRI) lesions. Lesions were classified as “early” (congenital), “late” neocortical (acquired after birth), and hippocampal sclerosis (HS).
Results: Of all patients, 78% were L, 6% R, 7% BD, and 9% BI. Right-handers with left lesions did …