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Rule-Based Categorization Deficits In Focal Basal Ganglia Lesion And Parkinson’S Disease Patients, Shawn W. Ell, Andrea Weinstein, Richard Ivry
Rule-Based Categorization Deficits In Focal Basal Ganglia Lesion And Parkinson’S Disease Patients, Shawn W. Ell, Andrea Weinstein, Richard Ivry
Psychology Faculty Scholarship
Patients with basal ganglia (BG) pathology are consistently found to be impaired on rule-based category learning tasks in which learning is thought to depend upon the use of an explicit, hypothesis-guided strategy. The factors that influence this impairment remain unclear. Moreover, it remains unknown if the impairments observed in patients with degenerative disorders such as Parkinson’s disease (PD) are also observed in those with focal BG lesions. In the present study, we tested patients with either focal BG lesions or PD on two categorization tasks that varied in terms of their demands on selective attention and working memory. Individuals with …
Focal Putamen Lesions Impair Learning In Rule-Based, But Not Information-Integration Categorization Tasks, Shawn W. Ell, Natalie L. Marchant, Richard B. Ivry
Focal Putamen Lesions Impair Learning In Rule-Based, But Not Information-Integration Categorization Tasks, Shawn W. Ell, Natalie L. Marchant, Richard B. Ivry
Psychology Faculty Scholarship
Previous research on the role of the basal ganglia in category learning has focused on patients with Parkinson’s and Huntington’s Disease, neurodegenerative diseases frequently accompanied by additional cortical pathology. The goal of the present study was to extend this work to patients with basal ganglia lesions due to stroke, asking if similar changes in performance would be observed in patients with more focal pathology. Patients with basal ganglia lesions centered in the putamen (6 left side, 1 right side) were tested on rule-based and information-integration visual categorization tasks. In rule-based tasks, it is assumed that participants can learn the category …