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An Ewas Of Dementia Biomarkers And Their Associations With Age, African Ancestry, And Ptsd, Mark W. Miller, Erika J. Wolf, Xiang Zhao, Mark W. Logue, Sage E. Hawn Jan 2024

An Ewas Of Dementia Biomarkers And Their Associations With Age, African Ancestry, And Ptsd, Mark W. Miller, Erika J. Wolf, Xiang Zhao, Mark W. Logue, Sage E. Hawn

Psychology Faculty Publications

Background

Large-scale cohort and epidemiological studies suggest that PTSD confers risk for dementia in later life but the biological mechanisms underlying this association remain unknown. This study examined this question by assessing the influences of PTSD, APOE ε4 genotypes, DNA methylation, and other variables on the age- and dementia-associated biomarkers Aβ40, Aβ42, GFAP, NfL, and pTau-181 measured in plasma. Our primary hypothesis was that PTSD would be associated with elevated levels of these markers.

Methods

Analyses were based on data from a PTSD-enriched cohort of 849 individuals. We began by performing factor analyses of the biomarkers, the results of which …


Trauma Exposure And Trauma Symptoms As Predictors Of Police Perceptions In Latinx Youths, Amanda Venta, Germán Cadenas, Alfonso Mercado, Luz M. Garcini, Melanie M. Domenech Rodríguez Jul 2022

Trauma Exposure And Trauma Symptoms As Predictors Of Police Perceptions In Latinx Youths, Amanda Venta, Germán Cadenas, Alfonso Mercado, Luz M. Garcini, Melanie M. Domenech Rodríguez

Psychology Faculty Publications

Objective: The Latinx immigrant youth population composes nearly a quarter of all children in the U.S. and are a high-risk group for police encounters. Based on perceptions of Latinxs as criminals, increased enforcement actions against Latinxs in the U.S., and failures of policing and police brutality in immigrants’ home countries, we expected that immigrants who reported increased trauma exposure and symptoms would have more negative perceptions of police. Method: This study utilized data from 107 recently immigrated Latinx youth to examine how trauma exposure (Child Trauma Screen) and symptoms (Child PTSD Symptoms Scale) related to perceptions of police (Criminal Sentiments …


Extended Functional Connectivity Of Convergent Structural Alterations Among Individuals With Ptsd: A Neuroimaging Meta-Analysis, Brianna S. Pankey, Michael C. Riedel, Isis Cowan, Jessica E. Bartley, Rosario Pintos Lobo, Lauren D. Hill-Bowen, Taylor Sato, Erica D. Musser, Matthew T. Sutherland, Angela R. Laird Jan 2022

Extended Functional Connectivity Of Convergent Structural Alterations Among Individuals With Ptsd: A Neuroimaging Meta-Analysis, Brianna S. Pankey, Michael C. Riedel, Isis Cowan, Jessica E. Bartley, Rosario Pintos Lobo, Lauren D. Hill-Bowen, Taylor Sato, Erica D. Musser, Matthew T. Sutherland, Angela R. Laird

Psychology Faculty Publications

Background: Post-traumatic stress disorder (PTSD) is a debilitating disorder defined by the onset of intrusive, avoidant, negative cognitive or affective, and/or hyperarousal symptoms after witnessing or experiencing a traumatic event. Previous voxel-based morphometry studies have provided insight into structural brain alterations associated with PTSD with notable heterogeneity across these studies. Furthermore, how structural alterations may be associated with brain function, as measured by task-free and task-based functional connectivity, remains to be elucidated.

Methods: Using emergent meta-analytic techniques, we sought to first identify a consensus of structural alterations in PTSD using the anatomical likelihood estimation (ALE) approach. Next, we generated functional …


A Preliminary Evaluation Of The Unified Protocol Among Trauma-Exposed Adults With And Without Ptsd, Caitlyn O. Hood, Matthew W. Southward, Christian Bugher, Shannon Sauer-Zavala Nov 2021

A Preliminary Evaluation Of The Unified Protocol Among Trauma-Exposed Adults With And Without Ptsd, Caitlyn O. Hood, Matthew W. Southward, Christian Bugher, Shannon Sauer-Zavala

Psychology Faculty Publications

The purpose of this study was to evaluate whether the Unified Protocol (UP)—a mechanistically transdiagnostic psychological treatment—provides benefit to individuals with a range of trauma histories, psychological difficulties, and diagnostic comorbidity. Using data from a sequential multiple-assignment randomized trial (SMART), this exploratory analysis included a sample of 69 community-recruited adults seeking outpatient mental health treatment. We examined reductions in anxiety and depressive symptoms and changes in aversive and avoidant reactions to intense emotions—the UP’s putative mechanism—first by comparing individuals with and without trauma histories and then specifically among participants with PTSD. Findings suggest that the UP may lead to similar …


Does Team Leader Gender Matter? A Bayesian Reconciliation Of Leadership And Patient Care During Trauma Resuscitations, Elizabeth D. Rosenman, Anthony Misisco, Jeffrey Olenick, Sarah M. Brolliar, Anne K. Chipman, Marie C. Vrablik, Georgia T. Chao, Steve W.J. Kozlowski, James A. Grand, Rosemarie Fernandez Jan 2021

Does Team Leader Gender Matter? A Bayesian Reconciliation Of Leadership And Patient Care During Trauma Resuscitations, Elizabeth D. Rosenman, Anthony Misisco, Jeffrey Olenick, Sarah M. Brolliar, Anne K. Chipman, Marie C. Vrablik, Georgia T. Chao, Steve W.J. Kozlowski, James A. Grand, Rosemarie Fernandez

Psychology Faculty Publications

OBJECTIVE: Team leadership facilitates teamwork and is important to patient care. It is unknown whether physician gender-based differences in team leadership exist. The objective of this study was to assess and compare team leadership and patient care in trauma resuscitations led by male and female physicians.

METHODS: We performed a secondary analysis of data from a larger randomized controlled trial using video recordings of emergency department trauma resuscitations at a Level 1 trauma center from April 2016 to December 2017. Subjects included emergency medicine and surgery residents functioning as trauma team leaders. Eligible resuscitations included adult patients meeting institutional trauma …


The Role Of Disgust In Posttraumatic Stress: A Critical Review Of The Empirical Literature, Christal L. Badour, Matthew T. Feldner Jul 2018

The Role Of Disgust In Posttraumatic Stress: A Critical Review Of The Empirical Literature, Christal L. Badour, Matthew T. Feldner

Psychology Faculty Publications

The current review provides a detailed analysis of the burgeoning literature examining the role of disgust in understanding posttraumatic stress symptomatology. Research in this area generally converges to suggest (1) posttraumatic stress is associated with the experience of elevated disgust, (2) individual differences in disgust vulnerabilities may relate to increased posttraumatic stress symptom levels, (3) retrospective report of peritraumatic disgust is related to posttraumatic stress symptom levels, and (4) posttraumatic stress symptom levels appear to be associated with increased disgust, including in response to traumatic event cues. Importantly, much of this research suggests observed relations between disgust and posttraumatic stress …


After-Action Reviews: The Good Behavior, The Bad Behavior, And Why We Should Care, John Crowe, Joseph A. Allen, Cliff Scott, Mackenzie Harms, Michael Yoerger Jul 2017

After-Action Reviews: The Good Behavior, The Bad Behavior, And Why We Should Care, John Crowe, Joseph A. Allen, Cliff Scott, Mackenzie Harms, Michael Yoerger

Psychology Faculty Publications

After action reviews have been a common learning and reliability intervention in organizations for decades, and though they have attracted the interest of scholars in recent years, researchers have yet to consider practitioner views of what makes these meetings more or less effective and to check their association with desired outcomes. The current multi-study begins by investigating what makes for good and bad after-action reviews (AARs) using an inductive approach and analyzing responses to open-ended questions about AAR attendee behaviors perceived as more or less effective by participants. Building upon Study 1, Study 2 focuses on the effects of good …


Organizational Identification: A Context-Specific Mitigating Resource Of Work–Family Conflict, Joseph A. Allen, John Crowe, Benjamin A. Baran, Cliff Scott Jan 2015

Organizational Identification: A Context-Specific Mitigating Resource Of Work–Family Conflict, Joseph A. Allen, John Crowe, Benjamin A. Baran, Cliff Scott

Psychology Faculty Publications

The tension between work and non-work life remains a critical issue in contemporary careers. This study explores the role of organizational identification (OI) in reducing work–family conflict (WFC) within demanding and high-stakes jobs in dynamic, uncertain and potentially dangerous contexts (e.g., firefighting). Survey data from 341 firefighters suggest that, congruent with conservation of resources theory and scarcity theory, OI may serve as a resource that mitigates WFC in these contexts. Additionally, the data suggest that the negative relationship between OI and WFC is stronger when trauma is low. For practice, this study provides important implications for employees in similar contexts …


The Effect Of Social Problem Solving Skills In The Relationship Between Traumatic Stress And Moral Disengagement Among Inner-City African American High School Students, Kendell L. Coker, Uduakobong N. Ikpe, Jeannie S. Brooks, Brian Page, Mark B. Sobell May 2014

The Effect Of Social Problem Solving Skills In The Relationship Between Traumatic Stress And Moral Disengagement Among Inner-City African American High School Students, Kendell L. Coker, Uduakobong N. Ikpe, Jeannie S. Brooks, Brian Page, Mark B. Sobell

Psychology Faculty Publications

This study examined the relationship between traumatic stress, social problem solving, and moral disengagement among African American inner-city high school students. Participants consisted of 45 (25 males and 20 females) African American students enrolled in grades 10 through 12. Mediation was assessed by testing for the indirect effect using the confidence interval derived from 10,000 bootstrapped resamples. The results revealed that social problem-solving skills have an indirect effect on the relationship between traumatic stress and moral disengagement. The findings suggest that African American youth that are negatively impacted by trauma evidence deficits in their social problem solving skills and are …


Alcohol Use And Trauma Exposure Among Male And Female Veterans Before, During, And After Military Service, Michelle L. Kelley, Jennifer Runnals, Matthew R. Pearson, Marinell Miller, John A. Fairbank, Va Mid-Atlantic Mirecc Women Veterans Workgroup Jan 2013

Alcohol Use And Trauma Exposure Among Male And Female Veterans Before, During, And After Military Service, Michelle L. Kelley, Jennifer Runnals, Matthew R. Pearson, Marinell Miller, John A. Fairbank, Va Mid-Atlantic Mirecc Women Veterans Workgroup

Psychology Faculty Publications

Background: The present study examined lifespan and combat-related trauma exposure as predictors of alcohol use among male and female veterans. Posttraumatic stress and depressive symptoms were examined as mediators of the effects of trauma exposure on alcohol use.

Methods: Data were examined from 1825 (1450 male, 375 female) veterans and active duty service members who took part in a multi-site research study conducted through the Department of Veterans Affairs Mid-Atlantic Mental Illness Research, Education and Clinical Center (VISN 6 MIRECC).

Results: For both men and women, depressive symptoms significantly mediated the effects of non-combat trauma exposure experienced before, during and …


An Examination Of Exposure To Traumatic Events And Symptoms And Strengths For Children Served In A Behavioral Health System Of Care, Melissa L. Whitson, Christian M. Connell, Stanley N. Bernard, Joy S. Kaufman Sep 2012

An Examination Of Exposure To Traumatic Events And Symptoms And Strengths For Children Served In A Behavioral Health System Of Care, Melissa L. Whitson, Christian M. Connell, Stanley N. Bernard, Joy S. Kaufman

Psychology Faculty Publications

The present study examined how exposure to traumatic events impacts children with severe emotional disturbance who are being served in a school-based system of care. Multilevel growth curve models were used to examine the relationships between a child’s history of traumatic events (physical abuse, sexual abuse, or domestic violence) and behavioral and emotional strengths, internalizing problem behaviors, or externalizing problem behaviors over 18 months. Results indicate that children receiving services (N = 134) exhibited increased emotional and behavioral strengths and decreased internalizing and externalizing problem behaviors from enrollment to 18 months follow-up. Children with a history of traumatic events improved …


Non-24-Hour Sleep-Wake Syndrome Following A Car Accident, D. B. Boivin, F. O. James, Jonathan Bruce Santo, O. Caliyurt, C. Chalk Jun 2003

Non-24-Hour Sleep-Wake Syndrome Following A Car Accident, D. B. Boivin, F. O. James, Jonathan Bruce Santo, O. Caliyurt, C. Chalk

Psychology Faculty Publications

The authors report the case of a 39-year-old sighted woman who displayed non-24-hour sleep–wake cycles following a car accident. The phase relationship between endogenous circadian markers such as plasma melatonin and 6-sulfatoxymelatonin rhythms and self-selected sleep times was abnormal. A laboratory investigation indicated that she was sensitive to bright light as a circadian synchronizer. MRI and brain CT scans were normal, but microscopic brain damage in the vicinity of the suprachiasmatic nucleus or its output pathways is plausible.


Efficacy Of Psychoeducational Group Therapy In Reducing Symptoms Of Posttraumatic Stress Disorder Among Multiply Traumatized Women, Hadar Lubin, Michelle Loris, John Burt, David Read Johnson Sep 1998

Efficacy Of Psychoeducational Group Therapy In Reducing Symptoms Of Posttraumatic Stress Disorder Among Multiply Traumatized Women, Hadar Lubin, Michelle Loris, John Burt, David Read Johnson

Psychology Faculty Publications

Objective: The role of group therapy in treatment of posttraumatic stress disorder (PTSD) has been traditionally restricted to issues of self-esteem and interpersonal relationships, rather than primary symptoms of the disorder. In this study, the authors examined the effectiveness of a 16-week trauma-focused, cognitive-behavioral group therapy, named Interactive Psychoeducational Group Therapy, in reducing primary symptoms of PTSD in five groups (N=29) of multiply traumatized women diagnosed with chronic PTSD. Method: The authors made assessments at baseline, at 1-month intervals during treatment, at termination, and at 6-month follow-up by using self-report and structured interview measures of PTSD and psychiatric symptoms. The …