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Functional Interplay Between Neurocognitive Decline And Risk Factors In Older Adults: A Multivariate Latent Growth Curve Model Of Risk, Rebecca Kathryn Macaulay
Functional Interplay Between Neurocognitive Decline And Risk Factors In Older Adults: A Multivariate Latent Growth Curve Model Of Risk, Rebecca Kathryn Macaulay
LSU Doctoral Dissertations
Alzheimer’s disease (AD) is a heterogeneous brain disease with multiple interacting risk factors, suggesting equifinality. Research indicates that the pathophysiological processes involved in AD are evident years prior to disease onset with significant variability in neurocognitive functioning being apparent during preclinical stages. Identification of individuals in preclinical stages is vital, as earlier interventions may prove more effective at ameliorating AD’s devastating effects. In this respect, clarifying relationships between risk factors and neurocognitive functioning in cognitively intact older adults can improve our understanding of mechanisms involved in preclinical AD, which may allow for earlier detection and intervention. The present study employed …
Trait Affective, Behavioral, And Cognitive Factors Of Anxiety And Depressive Symptoms In Children And Adolescents: A Hierarchical Model, Reanna Elise Whiting
Trait Affective, Behavioral, And Cognitive Factors Of Anxiety And Depressive Symptoms In Children And Adolescents: A Hierarchical Model, Reanna Elise Whiting
LSU Doctoral Dissertations
Researchers have proposed a vulnerabilities model that attempts to explain the similarities between the internalizing disorders via a hierarchical pathway of trait affectivity and cognitive factors among adults. The current study aimed to replicate and extend this model to symptoms of four internalizing disorders among youth: obsessions and compulsions, generalized anxiety/worry, social anxiety, and depression. Regression-based path analyses utilized data from a community sample of 105 youth aged 12-17 (67.6% female, 80% white, non-Hispanic). Results largely replicated prior models in the adult literature and overall supported a hierarchical paradigm. Trait negative affect and avoidant behavior predicted mid-tier cognitive vulnerabilities (anxiety …