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Role Of Cortisol In The Development Of Post-Traumatic Stress And Dysphoria, Devi Jayan
Role Of Cortisol In The Development Of Post-Traumatic Stress And Dysphoria, Devi Jayan
Dissertations (1934 -)
Exposure to a traumatic event is a significant predictor for the development of posttraumatic stress disorder (PTSD) and depression. Identification of specific risk factors for PTSD and depression after trauma exposure has been challenging due to comorbid and heterogeneous presentations of these conditions. Pre-existing research demonstrates reduced cortisol response (hypocortisolism) in chronic PTSD and an exaggerated cortisol response (hypercortisolism) in depression. The current longitudinal study examined cortisol response following a traumatic injury as a potential biomarker for deciphering specific risk for PTSD, depression, and PTSD depression comorbidity. Saliva samples for cortisol assay (post-injury cortisol) were collected from 172 trauma survivors …
Trauma Therapy For Very Young Children Living In Poverty: A Randomized Controlled Trial, Joanna Ruth Love
Trauma Therapy For Very Young Children Living In Poverty: A Randomized Controlled Trial, Joanna Ruth Love
Dissertations (1934 -)
This study used a randomized control design with immediate treatment and wait list control conditions to evaluate the efficacy of the New Hope program, a home-based, parent-and-child therapy program that has been developed for very young children living in poverty who experienced one or more potentially traumatizing events. Within a three-phase model of treatment, the New Hope program is designed to establish safety, build the caregiver child relationship, create a nurturing environment, teach coping skills, address trauma-related thoughts and feelings, and develop prosocial skills. Training in this program included discussions regarding the cultural implications of providing therapy services in the …
Development Of The Early Childhood Traumatic Stress Screen, Sara Elisabeth Harris
Development Of The Early Childhood Traumatic Stress Screen, Sara Elisabeth Harris
Dissertations (1934 -)
The study aimed to develop a brief screening instrument to assess symptoms associated with potentially traumatic experiences (PTE) in very young children (under 6). Potential items for the Early Childhood Traumatic Stress Screen (ECTSS) were sampled from each of the major content areas implicated in trauma. The items underwent a principle component analysis, which produced a 34-item screening measure with four reliable factors and one sub-scale assessing response style. All subscales and the overall trauma composite score significantly correlated with pre-established measures of traumatic stress in very young children, and a receiver operating characteristics curve analysis identified a cut-score with …
Long Term Effects Of Chronic Variable Stress Administered During Different Developmental Stages In Mice, Henry Boeh
Long Term Effects Of Chronic Variable Stress Administered During Different Developmental Stages In Mice, Henry Boeh
Dissertations (1934 -)
A number of studies have suggested that the occurrence of past trauma can increase an individual's chance of developing PTSD from a new traumatic experience later in life. Trauma that occurs during childhood appears to have a particularly strong effect on this risk increase. Furthermore, conditioned fear responses have been shown to incubate over extended periods of time in animal models. To further investigate the role these phenomena play in the development of PTSD, this study exposed juvenile and adult mice to 7 days of chronic variable stress (CVS). One month later, a Pavlovian delay fear conditioning procedure was used …