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Characterization Of The Hippocampal Acetylcholine System In A Rodent Model Of Fetal Alcohol Syndrome, Amy Elizabeth Perkins

Theses and Dissertations

Fetal alcohol spectrum disorders (FASD) are a major public health concern, as it is estimated that 2-5% of children are exposed to alcohol at some point during prenatal development. FASD have been shown to cause damage to multiple brain regions, but research shows that the hippocampus is especially sensitive to alcohol exposure. This damage to the hippocampus explains, in part, deficits in learning and memory that are hallmark symptoms of FASD. The acetylcholine neurotransmitter system plays a major role in learning and memory, and the hippocampus is one of its main targets. This experiment used a rodent model of Fetal …