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The Effects Of Escalated Fentanyl Intake On Decision-Making Dynamics, Trinity Shaver
The Effects Of Escalated Fentanyl Intake On Decision-Making Dynamics, Trinity Shaver
Theses and Dissertations--Psychology
Opioid Use Disorder is characterized partially as a decision-making disorder. Decision-making theories, such as habit theory and relative value theory, have aimed to better understand the shift in preference for drug over other alternatives. In order to compare these two contrasting theories, an allomorphic concurrent choice task will run in tandem with an escalation procedure. Male and female Sprague-Dawley rats were tested for choice differences in an allomorphic choice procedure. Reward dimensions, such as relative reward rate, were manipulated within sessions, and magnitude (remifentanil dose), was manipulated between sessions. To study the effects of escalated fentanyl intake on relative valuation, …
The Effects Of Extended Fructose Access On Relative Value And Demand For Fructose, Saccharin, And Ventral Tegmental Stimulation, Megan Halloran
The Effects Of Extended Fructose Access On Relative Value And Demand For Fructose, Saccharin, And Ventral Tegmental Stimulation, Megan Halloran
Theses and Dissertations--Psychology
Globally, food addiction (FA) is a growing area of research and is largely attributed to the availability of foods that are both energy dense and high in fats and sugars. Further, it has been suggested, that sugar and fat, when consumed frequently, have properties similar to drugs of abuse. While the validity of FA is questioned, researchers have drawn parallels between substance use disorder (SUD) and FA. For example, sugar binge models emphasize craving, withdrawal and binging as primary components of FA, which are also hallmarks of SUD. Additionally, both natural rewards, like sugars, and drug rewards act on the …
Targeting Food Selectivity In Young Children In A Preschool Classroom Using A Multi-Component Treatment Package, Christina Challed Hesley
Targeting Food Selectivity In Young Children In A Preschool Classroom Using A Multi-Component Treatment Package, Christina Challed Hesley
Theses and Dissertations--Early Childhood, Special Education, and Counselor Education
The purpose of the study was to evaluate the effectiveness of using a video model, graduated exposure (i.e., touch, smell, try, eat), and positive reinforcement to first increase food exploration, and then increase consumption of non-preferred foods in young children that exhibit food selectivity in a school setting. A multiple probe design across behaviors replicated across participants was used to evaluate the effectiveness of a treatment package. The treatment package consisted of a video model of each target behavior (touch, smell, try, eat) and positive reinforcement which included preferred foods and materials. The results indicated that the treatment package was …
Neurobehavioral Measurements Of Natural And Opioid Reward Value, Aaron Paul Smith
Neurobehavioral Measurements Of Natural And Opioid Reward Value, Aaron Paul Smith
Theses and Dissertations--Psychology
In the last decade, (non)prescription opioid abuse, opioid use disorder (OUD) diagnoses, and opioid-related overdoses have risen and represent a significant public health concern. One method of understanding OUD is as a disorder of choice that requires choosing opioid rewards at the expense of other nondrug rewards. The characterization of OUD as a disorder of choice is important as it implicates decision- making processes as therapeutic targets, such as the valuation of opioid rewards. However, reward-value measurement and interpretation are traditionally different in substance abuse research compared to related fields such as economics, animal behavior, and neuroeconomics and may be …
Cocaine Choice: A Novel Procedure For Investigating Neuronal Activation Mediating Cocaine Preference, Jonathan Jenn-Sheng Chow
Cocaine Choice: A Novel Procedure For Investigating Neuronal Activation Mediating Cocaine Preference, Jonathan Jenn-Sheng Chow
Theses and Dissertations--Psychology
Cocaine use disorder is a significant health problem, negatively impacting individuals afflicted. While preclinical self-administration research has provided invaluable insight into the neurobehavioral mechanisms that underlie cocaine abuse, cocaine use outside of the laboratory occurs within an environment where other goods are also available ubiquitously. Although there is an ever-increasing literature investigating drug vs. non-drug choice in rodent models and how alternative goods can compete with the subjective value of cocaine, the neurobiological mechanisms that are associated with cocaine preference remains largely unknown. Additionally, current drug vs. non-drug choice studies use procedures that confound preference with intake, such that preference …