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Psychology

University of Denver

Electronic Theses and Dissertations

Theses/Dissertations

2009

Behavioral medicine

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Trajectory Of Quality Of Life In Advanced Parkinson's Patients Receiving Bilateral Subthalamic Nucleus Deep Brain Stimulation, Karl S. Chiang Aug 2009

Trajectory Of Quality Of Life In Advanced Parkinson's Patients Receiving Bilateral Subthalamic Nucleus Deep Brain Stimulation, Karl S. Chiang

Electronic Theses and Dissertations

Quality of Life (QOL) in Parkinson's disease (PD) patients after Deep Brain Stimulation (DBS) neurosurgery generally improves between 3 to 24 months post-operatively. However, QOL beyond 2 year follow-up is generally unknown. This study examined the QOL in 16 advanced PD patients who received DBS at an average of 7.5 year follow-up with the Parkinson's Disease Questionnaire (PDQ-39). Participants had an average Disease Duration of 20.57 years (SD 5.7) and a mean Age of 63.50 (SD 8.05). Linear regression analyses suggested a constellation of changes involving Time, Age, and Disease Duration. As Time progressed since DBS intervention, the PDQ-39 Cognitions …