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Age-Related Functional Recruitment For Famous Name Recognition: An Event-Related Fmri Study, Kristy A. Nielson, Kelli Douville, Michael Seidenberg, John L. Woodard, Sarah K. Miller, Malgorzata Franczak, Piero Antuono, Stephen M. Rao
Age-Related Functional Recruitment For Famous Name Recognition: An Event-Related Fmri Study, Kristy A. Nielson, Kelli Douville, Michael Seidenberg, John L. Woodard, Sarah K. Miller, Malgorzata Franczak, Piero Antuono, Stephen M. Rao
Psychology Faculty Research and Publications
Recent neuroimaging research shows that older adults exhibit recruitment, or increased activation on various cognitive tasks. The current study evaluated whether a similar pattern also occurs in semantic memory by evaluating age-related differences during recognition of Recent (since the 1990s) and Enduring (1950s to present) famous names. Fifteen healthy older and 15 healthy younger adults performed the name recognition task with a high and comparable degree of accuracy, although older adults had slower reaction time in response to Recent famous names. Event-related functional MRI showed extensive networks of activation in the two groups including posterior cingulate, right hippocampus, temporal lobe …
Comparability Of Functional Mri Response In Young And Old During Inhibition, Kristy A. Nielson, Scott Aaron Langenecker, Thomas J. Ross, Hugh Garavan, Stephen M. Rao, Elliot Stein
Comparability Of Functional Mri Response In Young And Old During Inhibition, Kristy A. Nielson, Scott Aaron Langenecker, Thomas J. Ross, Hugh Garavan, Stephen M. Rao, Elliot Stein
Psychology Faculty Research and Publications
When using fMRI to study age-related cognitive changes, it is important to establish the integrity of the hemodynamic response because, potentially, it can be affected by age and disease. However, there have been few attempts to document such integrity and no attempts using higher cognitive rather than perceptual or motor tasks. We used fMRI with 28 healthy young and older adults on an inhibitory control task. Although older and young adults differed in task performance and activation patterns, they had comparable hemodynamic responses. We conclude that activation during cognitive inhibition, which was predominantly increased in elders, was not due to …