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A Translational Examination Of Alternative-Response Discrimination Training And Resurgence, Kaitlyn O. Browning Aug 2020

A Translational Examination Of Alternative-Response Discrimination Training And Resurgence, Kaitlyn O. Browning

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Individuals with neurodevelopmental disorders such as autism spectrum disorders often engage in severe forms of problem behavior. Reward-based behavioral interventions are highly effective at reducing levels of problem behavior and teaching more appropriate and adaptive alternative behaviors. Despite successful reduction in problem behavior during treatment, problem behaviors are susceptible to reoccurrence or relapse. Resurgence is a type of behavioral relapse that is particularly relevant to the treatment of problem behavior and may occur following the worsening of conditions of a more recently learned alternative behavior. That is, if the rewards that were used to teach the alternative behavior are removed …


A Temporal Information-Theoretic Model Of Suboptimal Choice, Paul J. Cunningham May 2020

A Temporal Information-Theoretic Model Of Suboptimal Choice, Paul J. Cunningham

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Humans and animals often make decisions not in their long-term best interest. In one example, called suboptimal choice, pigeons sacrifice food for food-predictive stimuli. The study of suboptimal choice can reveal insights into the role of reward-predictive stimuli in maladaptive decision-making that characterizes numerous behavioral disorders. However, there is currently little evidence that rats engage in suboptimal choice, thereby raising questions about the species-generality of suboptimal choice. According to the temporal information-theoretic model, developed in Chapter 2, suboptimal choice emerges when pigeons pay more attention to the bits of temporal information conveyed by food-predictive stimuli than the rate of food …


A Comparison Of Response-Contingent And Response-Independent Autoshaping Trials In Rats, Jenna E. Gaskins May 2020

A Comparison Of Response-Contingent And Response-Independent Autoshaping Trials In Rats, Jenna E. Gaskins

Theses and Dissertations

Autoshaping is a procedure, combining both operant conditioning and classical conditioning, used in animal training to jump-start a target behavior. Lepper and Petursdottir (2017) found that response-contingent pairings (RCP) were more effective than responseindependent pairings (RIP) in producing vocalizations in children with Autism Spectrum Disorder (ASD). RIP procedures entail a time-based intertrial interval (ITI) followed by the beginning of a trial, whereas RCP procedures include a response initiation period between the ITI and the trial. The current study compared RCP and RIP procedures to determine which one was more effective for acquisition of nose poking in rats. Number of days …


Influences Of Salvinorin A And Sex Differences On Depressive- And Anxiety-Like Behaviors In A Chronic Mild Stress Paradigm, Sarah Mitchell Apr 2020

Influences Of Salvinorin A And Sex Differences On Depressive- And Anxiety-Like Behaviors In A Chronic Mild Stress Paradigm, Sarah Mitchell

Theses

Kappa opioid receptors are colocalized with dopamine receptors and are frequently associated with depression, anxiety, stress, and drug use and abuse. KOR antagonism has widely been considered anti-depressive and anxiolytic in animal models while agonism is pro-depressive and anxiogenic. However, recent findings suggest that SalvA, a natural kappa agonist derived from a plant in the mint family, can reduce depressive- and anxiety-like behavior in rats. The current study investigated the effects of chronic mild stress on behavior, attenuation by SalvA, and sex differences. 52 Long-Evans rats, 26 males and 26 females, were exposed to six weeks of CMS. Animals received …


Age, Access, And Sweets-Motivation, Gehan Senthinathan Jan 2020

Age, Access, And Sweets-Motivation, Gehan Senthinathan

Theses and Dissertations (Comprehensive)

Availability can have profound influence on the consumption of foods and drinks. The 2-phase intermittent-continuous protocol (ICP) examines sucrose solution intake in two groups of rats and finds intermittent access significantly increases intake. In Phase I, rats receive intermittent or continuous access to a 4% sucrose solution, and with adults this results in a long-term elevation (a doubling) in the intermittent group. In Phase II, when rats are shifted to common sucrose schedule, this difference is maintained. Adult rats given 16% sucrose in Phase I do not differ in consumption, but in Phase II with 4% sucrose, an unexpressed elevation …