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The Prediction Of Personal Narrative On Features Of Recovery Among People With Schizophrenia-Spectrum Disorders, Beth Vayshenker
The Prediction Of Personal Narrative On Features Of Recovery Among People With Schizophrenia-Spectrum Disorders, Beth Vayshenker
Dissertations, Theses, and Capstone Projects
Among individuals with schizophrenia, research has demonstrated that in addition to the positive and negative symptoms characteristic of schizophrenia, the diminishment of the self also represents an important aspect of the illness (Lysaker & Lysaker, 2010). Research has confirmed that the self-experience, particularly as measured by the telling of one’s life story through the Scale to Assess Narrative Development (STAND), is linked to a variety of subjective and objective recovery outcomes from schizophrenia. While this association has been documented in different research studies, less is known about the ways in which personal narrative functions to predict recovery outcomes in a …
The (B)Link Between Amotivation And Dopamine In Psychosis: What Phasic Eye Blink Rate Reveals, Jessica Elaina Mcgovern
The (B)Link Between Amotivation And Dopamine In Psychosis: What Phasic Eye Blink Rate Reveals, Jessica Elaina Mcgovern
LSU Doctoral Dissertations
Motivation deficits (i.e., avolition or amotivation) are a cardinal feature of schizophrenia spectrum disorders (SSDs) and are linked to worse functional outcomes. Accumulating evidence implicates underactive dopamine responses in reward areas of the brain (e.g., striatum) in the etiology of amotivation. Phasic dopamine firing in the striatum purportedly has a role in increasing the perceived value of a potential reward that, in effect, helps “push” the organism toward initiating and persisting in the action to pursue rewards. Previous research has suggested that eye blink rate (EBR) may be a reliable and valid index of striatal dopamine. Amotivation (clinician-rated and self-reported) …
Attentional Deployment, Cognitive Control, And Reappraisal In Schizophrenia, Kyle Robert Mitchell
Attentional Deployment, Cognitive Control, And Reappraisal In Schizophrenia, Kyle Robert Mitchell
LSU Doctoral Dissertations
Recent studies posit that deficits in emotion regulation may lead to increased negative emotional experience in schizophrenia. While individuals with schizophrenia evidence a number of abnormalities in emotion regulation, it is unclear whether these deficits are discrete or related; furthermore, the mechanisms underlying these deficits are not clear. Cognitive control has been posited as an important mechanism supporting emotion regulation. The current study examined the relationship between attentional deployment and both lexical and self-reported indices of reappraisal, as well as the mediating role of cognitive control on this relationship in a sample of 22 individuals with psychotic disorders. A novel …
Neurocognitive Markers Of Cognitive Control In Schizophrenia And Functional Outcomes, Sephira Ryman
Neurocognitive Markers Of Cognitive Control In Schizophrenia And Functional Outcomes, Sephira Ryman
Psychology ETDs
Impaired cognitive function results in decreased objective quality of life and community functioning in schizophrenia, resulting in the largest indirect costs from the disease. Disrupted proactive cognitive control, a form of early selection and active goal maintenance, is hypothesized to underlie the broad cognitive deficits observed in patients with schizophrenia. The current study utilized novel electrophysiological (EEG) analytic approach to examine proactive and reactive cognitive control deficits in schizophrenia patients. Behavioral results highlight that patients exhibited a general reduction in reaction time across two multisensory cognitive control tasks, with selective deficits on proactive conditions relative to reactive conditions. The relative …
Effort-Related Decision Making In Comt Variant Mice: Pharmacological Studies And Genetic Susceptibility To Motivational Dysfunction, Suzanne Cayer
Effort-Related Decision Making In Comt Variant Mice: Pharmacological Studies And Genetic Susceptibility To Motivational Dysfunction, Suzanne Cayer
Honors Scholar Theses
Effort-related decision making tasks in animals can model motivational symptoms in humans, which are a set of symptoms spanning a multitude of neuropsychiatric disorders, such as major depressive disorder and the negative symptoms of schizophrenia. The present studies aimed to evaluate the effort-related effects of the Val158Met polymorphism of human catechol-methyltransferase (COMT), by testing mice carrying either the human COMT Val (n=8) or Met allele (n=8) with Wild-Type control mice (n=15) by using concurrent FR2 and FR4/pellet choice tasks in a touchscreen operant conditioning apparatus. The Val158Met polymorphism has been repeatedly associated with neuropsychiatric disorders, and the Val allele has …
The Human 'As-If'-Function And Its Loss In Schizophrenia, Thomas Fuchs
The Human 'As-If'-Function And Its Loss In Schizophrenia, Thomas Fuchs
Phenomenology Center Annual Symposium
No abstract provided.
Vocal Expression In Schizophrenia: Examining The Role Of Vocal Accommodation In Clinical Ratings Of Speech, Thanh P. Le
Vocal Expression In Schizophrenia: Examining The Role Of Vocal Accommodation In Clinical Ratings Of Speech, Thanh P. Le
LSU Master's Theses
Diminished vocal expressivity, defined in terms of a diminution in speech production and intonation/emphasis, is a chronic symptom in schizophrenia. On interview-based measures of vocal deficits, clinicians typically rate patients with schizophrenia 4 to 6 SDs below their non-patient peers. However, recent studies utilizing objective computerized measures have failed to observe vocal expressivity deficits that approach this level. It may be that vocal deficits can only be understood within the boundaries of dyadic exchanges during interview-based assessments. Vocal accommodation, or the degree to which vocal characteristics (i.e., mean F0) between interlocutors synchronize over time, has been linked to enhanced social …
The Relationship Between Religious Practices And Delusional Content Of Christians With Schizophrenia, Latasha Michelle Williams
The Relationship Between Religious Practices And Delusional Content Of Christians With Schizophrenia, Latasha Michelle Williams
Walden Dissertations and Doctoral Studies
Religious beliefs and practices are an important source of symptom relief for individuals with schizophrenia; however, it can also be a debilitating source of symptom exacerbation. This quantitative study examined the cognitions and religious life orientations of Christian individuals both with and without a diagnosis of schizophrenia, as measured by the Rust Inventory of Schizotypal Cognitions (RISC) and the Religious Life Inventory (RLI) to examine a baseline for healthy religious cognitions. The aberrant-salience and attribution theories were used to explore the relationship between psychotic stimuli and religious attributions. One hundred and thirty Christian individuals from an outpatient mental health facility, …
Identifying Subtypes Of Schizophrenia Through Differential Neurocognitive And Symptomatic Profiles, Brielle A. Marino
Identifying Subtypes Of Schizophrenia Through Differential Neurocognitive And Symptomatic Profiles, Brielle A. Marino
PCOM Psychology Dissertations
Schizophrenia has long been characterized solely by positive and negative symptoms of psychosis. It has also been typified by its widespread heterogeneity, which has impeded treatment outcomes. Previous attempts at reducing this heterogeneity via identifying symptom-based subtypes has been unhelpful and unreliable. More recently, cognitive deficits have been identified as prominent features of the disorder and are now included as necessary diagnostic criteria. The present study aimed to identify the unique relationships between cognitive deficits and psychotic symptoms and to establish subtypes based on these profiles. The findings suggest two distinct subtypes: (a) a deficit subtype wherein individuals display more …