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The Serotonin Transporter Gene Linked Polymorphic Region Is Associated With The Behavioral Response To Repeated Stress Exposure In Infant Rhesus Macaques, Simona Spinelli, Melanie L. Schwandt, Stephen G. Lindell, Markus Heilig, Stephen J. Suomi, James Dee Higley, David Goldman, Christina S. Barr Nov 2012

The Serotonin Transporter Gene Linked Polymorphic Region Is Associated With The Behavioral Response To Repeated Stress Exposure In Infant Rhesus Macaques, Simona Spinelli, Melanie L. Schwandt, Stephen G. Lindell, Markus Heilig, Stephen J. Suomi, James Dee Higley, David Goldman, Christina S. Barr

Faculty Publications

The short allele of the serotonin transporter linked polymorphic region (5-HTTLPR) moderates the effects of stress on vulnerability to mood and anxiety disorders. The mechanism by which this occurs may relate to differential sensitivity to stressful life events. Here we explored whether 5- HTTLPR and sex affected behavioral responses to repeated maternal separation in infant rhesus macaques. Behaviors were collected during the acute (Day 1) and the chronic (Days 2–4) phases of the separation, and the effects of duration of separation (acute vs. chronic), genotype (long/long vs. short allele), and sex (male vs. female) on behavioral responses were analyzed across …


Neural Responses To Infants Linked With Behavioral Interactions And Testosterone In Fathers, Patty X. Kuo, Joshua Carp, Kathleen C. Light, Karen M. Grewen Oct 2012

Neural Responses To Infants Linked With Behavioral Interactions And Testosterone In Fathers, Patty X. Kuo, Joshua Carp, Kathleen C. Light, Karen M. Grewen

Department of Child, Youth, and Family Studies: Faculty Publications

Few fMRI studies have investigated the brain-behavioral basis of parenting in human fathers. Ten fathers were videotaped and gave salivary testosterone samples while interacting with their 2–4 month old infants, and viewed video clips of their own infant and an unfamiliar age-, ethnicityand sex-matched other infant during an fMRI protocol. Infant stimuli activated a network of prefrontal and subcortical brain regions. Furthermore, a subset of these regions activated significantly more to own (OWN) than other (OTHER) infants. Finally, neural responses to OWN versus OTHER were linked with paternal sensitivity, paternal reciprocity, and testosterone. In sum, our results provide a novel …


Infant Responding To Joint Attention, Executive Processes, And Self-Regulation In Preschool Children, Amy V. Van Hecke, Peter Mundy, Jessica J. Block, Christine E.F. Delgado, Meaghan Venezia Parlade, Yuly B. Pomares, Jessica A. Hobson Apr 2012

Infant Responding To Joint Attention, Executive Processes, And Self-Regulation In Preschool Children, Amy V. Van Hecke, Peter Mundy, Jessica J. Block, Christine E.F. Delgado, Meaghan Venezia Parlade, Yuly B. Pomares, Jessica A. Hobson

Psychology Faculty Research and Publications

Infant joint attention is related to behavioral and social outcomes, as well as language in childhood. Recent research and theory suggests that the relations between joint attention and social–behavioral outcomes may reflect the role of executive self-regulatory processes in the development of joint attention. To test this hypothesis two studies were conducted. The first, cross-sectional study examined the development of responding to joint attention (RJA) skill in terms of increasing executive efficiency of responding between 9 and 18 months of age. The results indicated that development of RJA was characterized by a decreased latency to shift attention in following another …