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Arterial Pulse Wave Velocity And Cognition With Advancing Age, Merrill F. Elias, Michael A. Robbins, Marc M. Budge, Walter P. Abhayaratna, Gregory A. Dore, Penelope K. Elias Feb 2009

Arterial Pulse Wave Velocity And Cognition With Advancing Age, Merrill F. Elias, Michael A. Robbins, Marc M. Budge, Walter P. Abhayaratna, Gregory A. Dore, Penelope K. Elias

Maine-Syracuse Longitudinal Papers

We hypothesized that carotid-femoral pulse wave velocity (PWV), a marker of arterial stiffness, interacts with age such that the magnitude of associations between PWV and cognitive performance are greater with increasing age and that this interaction is observed despite adjustments for demographic variables, mean arterial pressure, and cardiovascular risk factors. PWV was estimated using applanation tonometry in 409 dementia- and stroke-free participants of the Maine-Syracuse Longitudinal Study (24 to 92 years of age; 62.3% women). Using linear regression analyses in a cross-sectional design, associations between PWV and age and the interaction of PWV and age were examined in relation to …


Chronic Kidney Disease, Creatinine And Cognitive Functioning, Merrill F. Elias, Penelope K. Elias, Stephen L. Seliger, Sriram S. Narsipur, Gregory A. Dore, Michael A. Robbins Jan 2009

Chronic Kidney Disease, Creatinine And Cognitive Functioning, Merrill F. Elias, Penelope K. Elias, Stephen L. Seliger, Sriram S. Narsipur, Gregory A. Dore, Michael A. Robbins

Maine-Syracuse Longitudinal Papers

Background. Non-dialysis-dependent chronic kidney dis- ease (CKD) is related to cognitive impairment. Previous studies have not explored the extent of impairment across multiple cognitive domains. We examined the range of specific cognitive abilities affected by CKD and whether the associations of CKD with cognition were eliminated by statistical control for cardiovascular disease correlates of CKD. Methods. We performed a community-based cross-sectional study with 923 individuals free from dementia and end-stage renal disease. Two groups were defined based on estimated glomerular filtration rate (eGFR): eGFR/min/1.73 m2 versus eGFR≥60 mL/min/1.73 m2. Out- come measures were scores from multiple clinical tests of specific …


The Influence Of Emotional Stimuli On Cognitive Performance In Relation To Delusion Intensity In Schizophrenia, Diana Orem Jan 2009

The Influence Of Emotional Stimuli On Cognitive Performance In Relation To Delusion Intensity In Schizophrenia, Diana Orem

Electronic Theses and Dissertations

Previous research has suggested that there are multiple psychological processes underlying delusional thought. While it appears that cognitive biases in certain reasoning and attention processes are related to delusion-proneness, the influence of emotion on these processes is not well understood. The overall objective of this study was to investigate the effect of emotional content on performance on tasks thought to measure attentional bias, preferential recall, and probabilistic reasoning in individuals with schizophrenia and demographically matched controls. In order to account for level of delusion-proneness, participants also completed a multidimensional measure of delusional thought. It was hypothesized that individuals with schizophrenia …