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Assessment Of The Discriminative Stimulus Effects And Time Courses Of Salvinorin A And Two Synthetic Salvinorin B Derivatives, Methoxylmethyl (Mom) And Ethoxymethyl (Eom), Ethers In Rats Trained To Discriminate U69,593, Lisa M. Bell
Masters Theses
Research regarding the psychopharmacology of salvinorin A, the main psychoactive ingredient in the hallucinogenic plant Salvia divinorum, has been motivated largely by a recent increase in its recreational use and widespread media attention focused on this plant and its extracts. In addition, there is considerable evidence that drugs acting on kappa opioid receptors (KOR) may have therapeutic potential in the treatment of some neuropsychiatric conditions, including drug dependence and mood disorders. Although the neuropharmacological actions of salvinorin A are well established, only a few studies have explored the behavioral effects of this substance in comparison to the KOR agonist, …
Of Mice And Mozart: Testing Spatial Reasoning And Memory Of Rats, Kaitlin O'Toole
Of Mice And Mozart: Testing Spatial Reasoning And Memory Of Rats, Kaitlin O'Toole
Honors Theses
An increase in spatial-temporal reasoning has been documented in the presence of Mozart's sonata K.448; this enhancement of physical and psychological activities is called the "Mozart Effect" (Hughes 2001). This effect has been recorded in humans and animals alike, and its influence reaches a myriad of applications including calming wild animals to increasing test scores in college students to lowering high blood pressure. Using a cheeseboard apparatus to test spatial reasoning in rats, this experiment recorded the results from maze tasks completed in the presence of sonata K.448 compared to trials completed in silence. Results showed a significant difference between …