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The Role Of Progesterone Receptor In Development Of Medial Prefrontal Cortex And Impulsive Behavior, Vanessa Costanzo

Psychology

Human behaviors are regulated by the complex functions of the brain and many behavioral disorders are assumed to be the result of alterations or deficits in neural function. Attention Deficit Hyperactivity Disorder (ADHD), characterized by differences in complex behaviors such as attention, memory and impulse control has been linked to alterations in dopaminergic activity in the medial prefrontal cortex (mPFC). Therefore, factors that regulate development of this region may be implicated in ADHD. For example, steroid hormones can alter fundamental processes of neural development through interaction with their nuclear receptors, which act as transcription factors. Progesterone receptor (PR) is transiently …