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A Longitudinal Investigation Of The Relationships Amongst Antibody Response To Influenza Vaccination, Affect, And Stress In The Elderly, Joanne Hash-Converse
A Longitudinal Investigation Of The Relationships Amongst Antibody Response To Influenza Vaccination, Affect, And Stress In The Elderly, Joanne Hash-Converse
Psychology
We examined the cross-sectional and longitudinal relationships amongst affect, stress exposure, and antibody (Ab) response to influenza inoculation in a healthy, elderly sample. We explored both efferent (CNS on immune activity) and afferent (immune activity on CNS function) pathways. Negative (NA) and positive (PA) affective states were examined in relation to Ab response, positing that high baseline NA (State, SNA, but not Trait, TNA) would predict reduced Ab response and that PA would predict enhanced response, and that the reduced Ab response in individuals displaying high baseline SNA would associate with decreases in NA. Moderator (for psychogenic and systemic stress) …