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LSU Doctoral Dissertations

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PTSD

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Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley Mar 2022

Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley

LSU Doctoral Dissertations

Post-traumatic stress disorder (PTSD) is associated with elevated allostatic load, nearly double the risk for metabolic syndrome, reduced hippocampal volume, and contextual memory processing deficits. Emerging evidence suggests that these stress effects may predispose individuals to the development of PTSD, and there is a known relationship between chronic stress and metabolic dysfunction. In this work, we utilized two rat models of PTSD to explore these connections. We used an acute predator odor stressor to investigate the relationship between PTSD-like behaviors and mitochondrial dysfunction in the hippocampus of rats, and we observed that conditioned place avoidance was associated with reduced mitochondrial …


A Comparison Of The Dsm-Iv And Proposed Dsm-V Ptsd Criteria For Youth: Factor Analyses Conducted With A Low Socioeconomic Status, Hurricane-Exposed Sample, Valerie Paasch Jan 2010

A Comparison Of The Dsm-Iv And Proposed Dsm-V Ptsd Criteria For Youth: Factor Analyses Conducted With A Low Socioeconomic Status, Hurricane-Exposed Sample, Valerie Paasch

LSU Doctoral Dissertations

Hurricane Katrina destroyed much of New Orleans, exposing residents to dangerous storms and significant flooding which resulted in the loss of many families’ homes and possessions. One of the most common psychological disorders experienced by disaster victims, both adult and child, is Posttraumatic Stress Disorder (PTSD). Given the debate over the appropriateness of applying adult DSM-IV-TR criteria to children and the current formulation of DSM-V criteria, this study further explored the presentation of PTSD symptomatology in a sample of 276 youth who experienced Hurricane Katrina. Proposed DSM-V criteria were assessed with participant responses on the UCLA PTSD Index for DSM-IV …


The Role Of Hurricane Exposure And Life Disruption As Predictors Of Child Post-Traumatic Stress Symptomatology Following Hurricane Katrina, Angie Lynn Pellegrin Jan 2009

The Role Of Hurricane Exposure And Life Disruption As Predictors Of Child Post-Traumatic Stress Symptomatology Following Hurricane Katrina, Angie Lynn Pellegrin

LSU Doctoral Dissertations

While many children emotionally recover following a disaster (Salzer & Bickman, 1999), possibly one-third of children will experience significant psychological distress or post-traumatic stress symptoms which cause interference with their daily school and home functioning (Vernberg, La Greca, Silverman, & Prinstein, 1996). Research supports the role that exposure, loss, and disruption play in increasing Post-Traumatic Stress Disorder (PTSD) severity in children following disasters (La Greca, Silverman, Vernberg, Prinstein, 1996; Verberg et al., 1996). However, there are no assessments or questionnaires that have investigated what type of events during and following a hurricane are most predictive of post-traumatic stress reactions. Using …


Environmental Effects On Adolescents Exposed To Hurricane Katrina, Karen Laslie Davidson Jan 2009

Environmental Effects On Adolescents Exposed To Hurricane Katrina, Karen Laslie Davidson

LSU Doctoral Dissertations

Adolescents in New Orleans were displaced by hurricane Katrina and returned to find their city devastated by this natural disaster. Although many studies have found a relationship between hurricane exposure and development of psychopathology, the current study evaluated this relationship within the context of protective and risk factors. Specifically, the current study evaluated whether community violence, parent support, and peer support moderated the relationship between hurricane exposure and adolescent PTSD or depression. Results found no relationship between hurricane exposure and adolescent depression. Although there was a main effect for hurricane exposure and PTSD, the proposed variables did not moderate this …