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Principles Of Sensorimotor Learning., Daniel M Wolpert, Jörn Diedrichsen, J Randall Flanagan
Principles Of Sensorimotor Learning., Daniel M Wolpert, Jörn Diedrichsen, J Randall Flanagan
Brain and Mind Institute Researchers' Publications
The exploits of Martina Navratilova and Roger Federer represent the pinnacle of motor learning. However, when considering the range and complexity of the processes that are involved in motor learning, even the mere mortals among us exhibit abilities that are impressive. We exercise these abilities when taking up new activities - whether it is snowboarding or ballroom dancing - but also engage in substantial motor learning on a daily basis as we adapt to changes in our environment, manipulate new objects and refine existing skills. Here we review recent research in human motor learning with an emphasis on the computational …
The Effect Of Dopamine Therapy On Ventral And Dorsal Striatum-Mediated Cognition In Parkinson's Disease: Support From Functional Mri., Penny A Macdonald, Alex A Macdonald, Ken N Seergobin, Ruzbeh Tamjeedi, Hooman Ganjavi, Jean-Sebastien Provost, Oury Monchi
The Effect Of Dopamine Therapy On Ventral And Dorsal Striatum-Mediated Cognition In Parkinson's Disease: Support From Functional Mri., Penny A Macdonald, Alex A Macdonald, Ken N Seergobin, Ruzbeh Tamjeedi, Hooman Ganjavi, Jean-Sebastien Provost, Oury Monchi
Brain and Mind Institute Researchers' Publications
The central aim of our study was to elucidate functions mediated by the ventral and dorsal striatum, respectively, to better understand the cognitive effects of dopamine replacement in Parkinson's disease. We proposed that the ventral striatum underlies general learning of stimulus associations, whereas the dorsal striatum promotes integration of various influences on selecting. In Parkinson's disease, dopamine depletion is substantially less notable in the ventral relative to the dorsal striatum, and therefore greater improvements are expected for dorsal striatum-mediated functions with dopamine replacement. Using a simple selection task, we found that dopamine replacement impaired encoding and facilitation of consistent stimulus-stimulus …
Negative Associations Between Corpus Callosum Midsagittal Area And Iq In A Representative Sample Of Healthy Children And Adolescents., Hooman Ganjavi, John D Lewis, Pierre Bellec, Penny A Macdonald, Deborah P Waber, Alan C Evans, Sherif Karama, The Brain Development Cooperative Group
Negative Associations Between Corpus Callosum Midsagittal Area And Iq In A Representative Sample Of Healthy Children And Adolescents., Hooman Ganjavi, John D Lewis, Pierre Bellec, Penny A Macdonald, Deborah P Waber, Alan C Evans, Sherif Karama, The Brain Development Cooperative Group
Brain and Mind Institute Researchers' Publications
Documented associations between corpus callosum size and cognitive ability have heretofore been inconsistent potentially owing to differences in sample characteristics, differing methodologies in measuring CC size, or the use of absolute versus relative measures. We investigated the relationship between CC size and intelligence quotient (IQ) in the NIH MRI Study of Normal Brain Development sample, a large cohort of healthy children and adolescents (aged six to 18, n = 198) recruited to be representative of the US population. CC midsagittal area was measured using an automated system that partitioned the CC into 25 subregions. IQ was measured using the Wechsler …