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University of South Florida

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Smoking

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Assessing The Impacts Of Sensorimotor Stimuli And Nicotine Content On Cravings And Other Outcomes Of E-Cigarette Use, Amanda M. Palmer Jun 2020

Assessing The Impacts Of Sensorimotor Stimuli And Nicotine Content On Cravings And Other Outcomes Of E-Cigarette Use, Amanda M. Palmer

USF Tampa Graduate Theses and Dissertations

As use rates of e-cigarettes continue to rise, especially among cigarette smokers, there remains concern that “dual use” may lead to increased dependence and hinder smoking cessation efforts. At the same time, emerging evidence suggests clinical efficacy of e-cigarettes. The role of nicotine must be considered, in addition to non-pharmacologic influences, such as expectancies or conditioned reinforcers. Sensorimotor stimuli associated with drug delivery have been demonstrated to produce cigarette and e-cigarette craving reduction, even without the nicotine. The purpose of the present study was to parse the influences of nicotine and sensorimotor delivery on various outcomes of e-cigarette use, including …


Parsing The Influences Of Nicotine And Expectancies On The Acute Effects Of E-Cigarettes: A Balanced-Placebo Experiment, Amanda M. Palmer May 2017

Parsing The Influences Of Nicotine And Expectancies On The Acute Effects Of E-Cigarettes: A Balanced-Placebo Experiment, Amanda M. Palmer

USF Tampa Graduate Theses and Dissertations

E-cigarette use has been increasing in recent years, and its ultimate public health impact is still unknown. In order to assess the addictive liability of these products, research is needed to investigate the roles of nicotine and other factors on psychological and physical effects of “vaping.” The goal of the current study was to investigate the role of expectancies, nicotine delivery, and their interactions on the effects of e-cigarette use via a balanced-placebo experiment. In this design, drug dosage (contains nicotine or not) was crossed with instructions (told nicotine or non-nicotine) during ad-lib e-cigarette use sessions by 128 current e-cigarette …


Effects Of Nicotine Withdrawal On Motivation, Reward Sensitivity And Reward-Learning, Jason A. Oliver Jan 2015

Effects Of Nicotine Withdrawal On Motivation, Reward Sensitivity And Reward-Learning, Jason A. Oliver

USF Tampa Graduate Theses and Dissertations

Research on addictive behavior has traditionally emphasized the role that primary reinforcing effects of drugs of abuse plays in the development and maintenance of dependence. However, contemporary behavioral economic theory and animal models of nicotine dependence suggest the need for greater attention to the impact that response to alternative rewards may have on smoking behavior. The present study sought to investigate the impact of nicotine withdrawal on self-report, behavioral and neural indices of motivation, immediate response to rewards and the capacity to learn and modify behavior in response to positive and negative feedback. Heavy smokers (n = 48) completed two …


Self-Control Depletion And Nicotine Deprivation As Precipitants Of Smoking Cessation Failure: A Human Laboratory Model, Bryan Heckman May 2014

Self-Control Depletion And Nicotine Deprivation As Precipitants Of Smoking Cessation Failure: A Human Laboratory Model, Bryan Heckman

USF Tampa Graduate Theses and Dissertations

The need to understand the reinforcing properties of smoking and potential precipitants of relapse is exemplified by evidence that relapse rates exceed 95%. The Self-Control Strength model, which proposes that self-control is dependent upon limited resources and susceptible to fatigue, may offer insight into the relapse process. Indeed, there is empirical support that engaging in a task that requires self-control, relative to a comparable control, results in performance decrements on subsequent self-control tasks. The primary goal of the current study was to test whether self-control depletion (SCD) may serve as a novel antecedent for cessation failure, using a validated laboratory …


Responding To Tobacco Craving: Acceptance Versus Suppression, Erika B. Litvin Jan 2011

Responding To Tobacco Craving: Acceptance Versus Suppression, Erika B. Litvin

USF Tampa Graduate Theses and Dissertations

Most treatments for substance use disorders (SUDs) are based on a model that craving is a primary cause of relapse, and therefore they emphasize skills for preventing and reducing craving. Acceptance and Commitment Therapy (ACT) provides a theoretical rationale for "acceptance" of drug-related thoughts and cravings, and proscribes suppression, a more intuitive and commonly used coping strategy. However, it remains largely unknown whether various coping strategies differentially affect craving intensity, drug use behavior, or other relevant outcomes during a craving episode. Using a randomized, between-subjects design (acceptance-based coping, suppression-based coping, or no coping instructions/control), the current study compared the effect …