Digital Commons Network^™

Cerebellar Vermis: Contributions To The Phenomenology Of Obsessive-Compulsive Disorder, Moriah Eve Stern

Psychology ETDs

Background: Current neurocognitive models of obsessive-compulsive disorder (OCD) implicate dysfunction in top-down inhibitory control mechanisms. Research supports alteration in the functional activity of cortico-basal ganglia-thalamo-cortical loops in OCD, as well as the inferior parietal region, posterior medial cortex, thalamus and cerebellum. The cerebellum, once only known as a region of motor coordination, is now accepted as being highly involved in cognitive regulation as well. Emerging evidence of connectivity between the posterior cerebellum and areas of the brain related to inhibitory functioning, including the basal ganglia, prefrontal, and inferior parietal regions, suggests a potential cerebellar role in OCD-symptomology. In fact, in …