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Reinforcement Learning In Individuals At Risk For Alzheimer's Disease, Christina Marie Figueroa

Master's Theses (2009 -)

Explicit memory is the hallmark of impairment in Alzheimer’s disease (AD) while implicit memory has mixed task-dependent results. Models of memory processes have posited that hippocampal function is sensitive to reinforcement learning (RL), which involves both explicit and implicit memory. The hippocampus is also vital for the transfer of learned associations to novel situations. Nevertheless, RL paradigms have been underutilized in assessing memory processes in individuals at risk for AD, which may aid in early identification of cognitive decline. Thirty-six apolipoprotein-E (APOE) genotyped older adults (Male n=8; Mage=80; Meducation=15 years) performed word stem completion, word recognition, and RL tasks. The …