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Double Trouble: The Development And Use Of A Novel Spatial Memory Task To Study Depression In A Female Rodent Model, Ekaterina L. Koelliker

Honors Theses

Preclinical rodent models of depression are important for improving our understanding of the behavioral and neurobiological implications of the disorder. However, the current behavioral assays used to assess depressive symptoms in rodents have substantial shortcomings; they are basic, test animals individually, and do not evaluate animals for extended periods. The primary goals of the present study, which was divided into two experiments, were to develop a novel task that could be used to study spatial memory and to apply the task to rodent models of depression. Both experiments used a circular arena with 10 identical jars to analyze the spatial …

Characterizing Cellular Stress, Hippocampal Function, And Behavior In A Novel Rat Model Of Alzheimer's Disease, Anne A. Schulman

Honors Theses

Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that affects over 5 million individuals in the United States alone. While AD is primarily thought of as a disease that destroys neural networks required for memory recall and formation, AD also cause impairment in emotional regulation, cognitive flexibility, and executive function pathways. The cause of AD is unknown; however, the allele ApoE4 has been identified as a risk factor for the onset of AD. ApoE4 provides a valuable opportunity to study AD through animal models. This thesis utilized a human ApoE4 transgenic rat model (hApoE4) to investigate the biological and behavioral …

The Role Of Socioeconomic Status In Cognition And Brain Health Across The Lifespan, Erica Chung

Honors Theses

Disparities in cognition are inevitable throughout the lifespan due to socioeconomic gaps. Individuals of lower socioeconomic status (SES) may have fewer access to environmental resources, especially with regard to education, than individuals of higher socioeconomic status. Differences in available resources from a young age may affect brain development, leading to detriments in cognition and behavior, further impacting socioeconomic success in adulthood. In the present study, we modeled the development of the dorsolateral prefrontal cortex (DLPFC) and changes in cognitive function throughout the life trajectory in the Nathan Kline Institute for Psychiatric Research Rockland Sample. The DLPFC volume was predicted to …

Assessing A Two-Hit Model Of Schizophrenia: Prenatal Choline Deficiency And Induced Hypofunction Of Nmda Receptors In Male And Female Long Evans Rats, Samuel Gray, Samuel W. Gray

Honors Theses

Choline is an essential dietary nutrient essential to the development and function of the central nervous system. Prenatal choline deficiency alters hippocampal development as well as acetylcholine metabolism, leading to cognitive impairments and attentional and sensory processing deficits into adulthood. MK-801 is an NMDA receptor antagonist frequently used in rodent models of neuropsychiatric conditions, particularly schizophrenia. Acutely and sub- chronically, it causes hyperlocomotion and social withdrawal. One primary goal of the present study were to investigate prenatal choline deficiency induces a biological vulnerability to the motor deficits, anhedonia, and social impairment precipitated by low-dose sub-chronic MK-801 administration in adulthood. Another …

Executive Function Deficit As A Precursor To Memory Impairments In Hapoe4 Transgenic Rats, Kaitlin Mcmanus

Honors Theses

The hApoE4 allele is one of the strongest genetic risk factors for Alzheimer’s disease (AD). It underlies amyloid-bdeposits and neurofibrillary tangles, the two hallmarks associated with AD pathology, and is subsequently associated with AD symptomology. Despite its importance, no rat animal studies to date use hApoE4 knock-ins. In addition to this deficit in the field of AD literature, the vast majority of AD studies focus on memory, even though executive function deficits may precede memory impairments in AD, and may be a predictor of AD development. Thus, the present study addressed these gaps in AD research by investigating the behavioral …

The Impacts Of Discrimination On Mental And Physical Health, Mahal Alvarez-Backus

Honors Theses

The present studies investigated the role of campus climate and discrimination on college students’ mental and physical health. Young adults completed measures that assessed their perceptions of campus climate, sense of belonging, depressive symptoms, anxiety levels, sleep quality, physical health symptoms, and experiences with discrimination. Despite the fact that there were not any differences in physical health or sleep quality, there were significant differences in phycological health, specifically with depressive symptoms. Across both studies, there were significant group differences in mental health, particularly that students of color reported higher levels of depressive symptoms than white students. Having empathetic faculty was …

The Anonymous Truth: Honesty And Hostility In Public And Private Online Settings, Grace S. Carroll

Honors Theses

Three studies were conducted to understand the relationship between honesty and hostility in public and private online settings. Study one analyzed a college’s public and private online forums and examined post frequency. Related to study one, study two examined the usage of these forums, and current and past social and political issues. Study one found the public forum comprised of general announcements, while the private forum hosted random jokes/statements, negative posts targeting specific people, and personal reflections. Study two’s results indicated the private forum was used more often than the public forum and race was the prevailing social and political …

America's National Parks And The Anthropocene: Addressing The Present To Accommodate The Future In Acadia National Park, Sophie A. Swetz

Honors Theses

In 2000, atmospheric chemist, Paul J. Crutzen, and limnologist, Eugene Stoermer, formally proposed the idea of “the Anthropocene,” a new geologic epoch in which humans are the dominant force shaping the Earth. To claim the Anthropocene's existence is to declare that human actions have altered the Earth in such a way that geologic indicators render it a distinct epoch in the stratification of geologic time. This new epoch emerges as a consequence of increased technological development employed to accommodate an anthropocentric human existence. That is, rapid advancements in technology have driven the transformation from a primarily naturally controlled planet to …

Health Care Agency: Statewide Awareness Of Patient-Centered Care In Maine’S Mental Health Care Facilities, Holly Hogan A

Honors Theses

This research project focuses on patient-centered care (PCC) in the context of inpatient acute psychiatric units. Hospitals have been claiming their renewed outlooks on health-care via PCC. It has become an increasingly popular term to use on hospital websites and in presidential statements. The technologies and practices surrounding psychiatric care have evolved in such a way that patients are more welcomed to have an input in their care. This project discusses the discourse around PCC at Mental Health Care Facilities in Maine. There is no consensus on the definition; the meanings ascribed to it are derived from the individual institutions. …

Are The Brain And The Mind One? Neuromarketing And How Consumers Make Decisions, Emily Glaenzer

Honors Theses

Neuromarketing utilizes brain-imaging technology, such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) machines, to understand consumers’ neurological responses to marketing stimuli. In this paper, I demonstrate how neuromarketing connects to the history of subliminal messaging and our current neuro-obsessed culture (neuroculture). These factors affect how critics view neuromarketing and the implications involved for the future of this study. I hypothesize that, when used correctly, neuromarketing can initiate a new section of the marketing world that will serve as a useful component to more traditional marketing practices. By taking away social bias and inaccurate answers present in market research, …

The Influence Of Normative Feedback On Stigma Of Mental Health, Carly A. Taylor

Honors Theses

The National Alliance on Mental Illness (NAMI; 2012) reports that the greatest barrier preventing college students from seeking help for a mental illness is stigma. Previous research has yet to develop an effective stigma reduction intervention targeting college students.Therefore, the purpose of the following research was to examine whether the administration of personalized normative feedback (PNF) could reduce personal stigma and correct the perception that others stigmatize mental illness. It was hypothesized that participants at baseline would expect others to hold more stigmatizing views compared to themselves. In order to correct this misperception and reduce stigma, half of the participants …

School Gardens: Cultivating A Child’S Nutritional Habits, Environmental Knowledge, And Sustainability Practices, Jeffrey Meltzer

Honors Theses

School gardens have existed since the late nineteenth century and today are becoming increasingly popular in many parts of the world, including where I studied in Maine and Australia (AUS). Multiple organizations support school gardens in Maine, including the Maine School Garden Network, which has over 125 registered school gardens. In AUS, the Stephanie Alexander Kitchen Garden Foundation primarily supports the school garden movement and has over 800 registered school gardens. While many researchers have studied school gardens, few have compared two countries, focused on environmental sustainability, or investigated Maine in particular. This thesis combines information from literature reviews, and …

The Importance Of Fitting In: Drinker Status, Social Inclusion, And Well-Being In College Students, Molly B. Hodgkins

Honors Theses

These three studies examined the relationship between drinker status, well-being, and social inclusion in a college population, specifically seeking to discover why and how drinkers are happier than abstainers. In the first study, an existing longitudinal data set was used to compare the happiness of drinkers and non-drinkers, as well as ascertain if year in school was a factor. Drinkers were significantly happier than non-drinkers upon completion of their first semester freshman year, but this difference was not significant when the students were assessed one year later. Study 2 extended Study 1 by examining social factors as potential mediators of …

The Influence Of Framing Effects And Regret On Health Decision-Making, Sarah Falkof

Honors Theses

This study investigates methods for influencing decision-making regarding preventative vaccine shots. Specifically, the research assessed the influence of message framing on regret and future action likelihood. In Experiment 1, participants read information about an available vaccine shot that was either framed positively or negatively. Participants were told whether they decided to get the shot (action) or not get the shot (inaction) and rated their feelings of regret after being told they got sick, regardless of their decision. Results showed that participants who read the positively framed information experienced more regret overall than participants who read the information with the negative …

The Effect Of Identification Style On Confidence Inflation In Eyewitness Testimony, Kelsey L. Stratton

Honors Theses

The purpose of this study is to determine whether confidence inflation in eyewitness testimony can be altered by the effects of self-perception and public commitment, as manipulated by identification style. In order to investigate these specific effects, identifications and confidence reports were made using both private and public methods. Additionally, target-present and target-absent lineups were used in order to assess their relative effects and to control participant accuracy.

Results revealed that the best confidence-accuracy correlations, as determined by a comparison from pre-lineup measures, were a result of post-lineup, private identifications. This indicates that self-perception may be more responsible for confidence …

Therapeutic Discourse And The American Public Philosophy: On American Liberalism's Troubled Relationship With Psychology, Clifford D. Vickrey

Honors Theses

I explore the main currents of postwar American liberalism. One, sociological, emerged in response to the danger of mass movements. Articulated primarily by political sociologists and psychologists and ascendant from the mid-fifties till the mid-seventies, it heralded the "end of ideology." It emphasized stability, elitism, positive science and pluralism; it recast normatively sound politics as logrolling and hard bargaining. I argue that these normative features, attractive when considered in isolation, taken together led to a vicious ad hominem style in accounting for views outside the postwar consensus. It used pseudo-scientific literature in labeling populists, Progressives, Taft conservatives, Goldwaterites, the New …

No, I’M Really, Really Bad At Math: Competition For Self-Verification, Alexandra E. Wesnousky

Honors Theses

In their theory of self-verification, Swann and Read’s (1981) postulate that people like feedback that is consistent with their self-concept. Researchers have yet to examine what happens when two individuals are both seeking feedback from each other to verify their self-concept on the same domain. When individuals are competing against someone to verify a similarly held self-concept, they should try to seek more polarized feedback, especially when the domain is highly important. In two experiments, participants expected to receive computer feedback on their responses to identity-related questions, either based on their own responses or on how they compared to the …

Immunological Effects Of Written Disclosure In Athletes, Kristen Thatcher

Honors Theses

Many studies have demonstrated the health benefits of written disclosure of traumatic or stressful events. These benefits include improved psychological well-being, fewer health clinic visits, shorter hospital stays after surgery, and increased immune function. In athletes, high immune function is necessary to ward off illness during training and competition, but much research has shown that athletes tend to have lowered immune function. Therefore, writing about traumatic events may be a way for athletes to remain healthy during their seasons. To test this hypothesis, 21 varsity athletes and 15 individuals who exercised less than three hours per week participated in the …

Anhedonia And Depression: Anticipatory, Consummatory, And Recall Deficits, Kaitlin Hanley

Honors Theses

Current conceptions of anhedonia as a key symptom of depression do not consider the importance of anticipatory, consummatory, and recall deficits involved in anhedonia. Sixty-one depressed and non-depressed, college-student participants provided reports of anticipated pleasure to tasting chocolates, tasted chocolates and rated their experience of pleasure, and provided recalled reports of pleasure to the experience one day later. Results demonstrated a deficit in the ability to anticipate experiencing pleasure for depressed participants when compared to non-depressed controls, however, their reports of consummatory pleasure and recalled pleasure did not differ significantly from non-depressed control participants. This study suggests that actual experiential …

Visual Expectations: Using Machine Learning To Identify Patterns In Psychological Data, Skyler Place

Honors Theses

The goal of this project was to utilize the tools of machine learning to evaluate the data obtained through experiments in psychology. Advanced pattern finding algorithms are an effective approach to analyzing large sets of data, from any domain of science. Consequently, we have a psychological question and hypothesis, and a separate machine learning technique to assess these claims. The realm of psychology that I focused on is visual cognition, and how an individual's knowledge affects how they see the world. This alteration of visual data is a part of perception -when the brain enhances the data coming in from …

Power And The Social Order: Sex Role Stereotyping In Children's Television, Christine Burke

Honors Theses

The aim of this study is to offer an assessment of the common themes in feminist, Lacanian psychoanalytic and deconstructionist theory. It will then discuss the degree to which these three discourses allow us to grasp the implications of the political socialization which occurs through television programming directed primarily at children.

There are points of commonality and discordance between these approaches. My aim will not be to make the argument that one approach is best, nor to arrive at a final synthesis. Rather, I construe these theoretical approaches as different lenses through which we can apprehend and evaluate the messages …